Abstract:Hemodiafiltration (HDF) achieves a more efficient reduction of the uremic toxic load compared to standard high‐flux hemodialysis (HF‐HD) by virtue of the combined diffusive and convective clearances of a broad spectrum of uremic retention solutes. Clinical trials and registry data suggest that HDF improves patient outcomes. Despite the acknowledged need to improve survival rates of dialysis patients and the survival benefit HDF offers, there is little to no utilization in some countries (such as the US) in pre… Show more
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