Swine Models of Aneurysmal Diseases for Training and Research

Large Animal Models of Cardiovascular Disease: From Training to Translation

“…The development of new tools or therapeutic strategies for the management of IA must be explored in a preclinical setting before translation to a clinical scenario can be performed. Blanco-Blázquez et al describe two surgically created aneurysmal swine models that show encouraging results in the research field of nonruptured aneurysms and training in neuroradiology techniques 5 . Although the described models do not completely replicate the physiopathological circumstances involved in the development of aneurysms in terms of hemodynamics, they proved to be equivalent to the condition observed in humans.…”

“…Although the described models do not completely replicate the physiopathological circumstances involved in the development of aneurysms in terms of hemodynamics, they proved to be equivalent to the condition observed in humans. Accordingly, it was appropriate for medical professionals to practice different endovascular procedures as well as useful for researchers to explore new therapeutic options 5 .…”

Large Animal Models of Cardiovascular Disease: From Training to Translation

“…The development of new tools or therapeutic strategies for the management of IA must be explored in a preclinical setting before translation to a clinical scenario can be performed. Blanco-Blázquez et al describe two surgically created aneurysmal swine models that show encouraging results in the research field of nonruptured aneurysms and training in neuroradiology techniques 5 . Although the described models do not completely replicate the physiopathological circumstances involved in the development of aneurysms in terms of hemodynamics, they proved to be equivalent to the condition observed in humans.…”

“…Although the described models do not completely replicate the physiopathological circumstances involved in the development of aneurysms in terms of hemodynamics, they proved to be equivalent to the condition observed in humans. Accordingly, it was appropriate for medical professionals to practice different endovascular procedures as well as useful for researchers to explore new therapeutic options 5 .…”