The microstructure of annealed AISI Type 304 and Type 316 stainless steels has been characterized by transmission electron microscopy as a function of fast reactor irradiation at fluence levels from 4 x 1021 to 7 x 1022 n/cm2 (E > 0.1 MeV) and at irradiation temperatures from 370 to 700°C. Several irradiation produced defect types were found: voids, Frank faulted loops, perfect loops, dislocation networks, and precipitates. Void number density obeys a power law relationship to fluence. wherein the exponent increases with increasing temperature and has a mean value near unity; The void size is nearly •independent of fluence and increases with increasing temperature. The upper limit irradiation temperature for void formation is about 650 to 700°C. The density and size of Frank faulted loops followed.trends similar to those found for voids to temperatures of ~ssooc where unfaulted loops, perfect loops, and dislocation networks coexist. These experimental results do not confirm predictions of recently advanced models of void formation. The major deficiency of these models appears• to be the nucleation rate. Accordingly, empirical nucleation rates were used to formulate a diffusion controlled void growth model. This model was found to closely describe experimentally determined void growth kinetics .