Sweet Syndrome in the Pediatric Population

McClanahan, Danielle; Funk, Tracy; Small, Alison

doi:10.1016/j.det.2021.12.005

Cited by 6 publications

(6 citation statements)

References 48 publications

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“…Sweet syndrome typically occurs in the fourth to seventh decade of life. However, the condition may rarely occur in children, with less than 8% of cases diagnosed in the pediatric population, and with about 80 published cases reported in the literature 10,11 . Importantly, the development of Sweet syndrome in the first 6 weeks of life is more likely to be associated with an underlying systemic or genetic condition, which was the case with our patient 10 …”

Section: Discussionmentioning

confidence: 52%

“…However, the condition may rarely occur in children, with less than 8% of cases diagnosed in the pediatric population, and with about 80 published cases reported in the literature. 10,11 Importantly, the development of Sweet syndrome in the first 6 weeks of life is more likely to be associated with an underlying systemic or genetic condition, which was the case with our patient. 10 IBD may be associated with extra-intestinal manifestations, including arthritis, uveitis, erythema nodosum, pyoderma gangrenosum, aphthous stomatitis, primary sclerosing cholangitis, and calcium oxalate kidney stones.…”

Section: Discussionmentioning

confidence: 53%

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A case of mevalonate kinase deficiency, neonatal Sweet syndrome, and inflammatory bowel disease

Esfandiari,

Vandyke,

Porter

et al. 2023

Pediatric Dermatology

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Mevalonate kinase deficiency is a group of rare metabolic autoinflammatory disorders that present with recurrent fevers, abdominal pain, arthralgias, adenopathy, and a variety of cutaneous manifestations. The skin findings may mimic cellulitis, erythema elevatum diutinum, IgA vasculitis, and Sweet syndrome, and there is often a morbilliform or urticarial rash and aphthous stomatitis. Mevalonate kinase deficiency is one of the identified monogenic variants that can cause very early onset inflammatory bowel disease (IBD). We present a rare case of a patient with mevalonate kinase deficiency, neonatal Sweet syndrome, and infantile‐onset IBD, who has been successfully treated with canakinumab therapy.

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Section: Discussionmentioning

confidence: 52%

Section: Discussionmentioning

confidence: 53%

A case of mevalonate kinase deficiency, neonatal Sweet syndrome, and inflammatory bowel disease

Esfandiari,

Vandyke,

Porter

et al. 2023

Pediatric Dermatology

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“…Vakaların yarıya yakınında da bir neden gösterilememektedir. 5,6 SS tanısı majör ve minör tanı kriterleri temel alınarak konulmaktadır (Tablo 1). Tanı kriterlerindeki majör kriterlerin tamamına ek olarak 4 minör kriterden en az 2'sinin varlığı SS'de tanı koydurucudur.…”

Section: Discussionunclassified

Sweet Syndrome in a Pediatric Patient with Ulcerative Colitis

BAŞARAN,

BOTSALI,

ARSLAN

et al. 2024

Turkiye Klinikleri J Pediatr

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Akut ateşli nötrofilik dermatoz olarak da bilinen Sweet sendromu (SS) hassas eritematöz plaklar veya nodüller, ateş, artralji, oftalmolojik belirtiler, baş ağrısı, oral veya genital lezyonlarla seyreden nadir bir hastalıktır. 1 Etiyolojisinde inflamatuar, otoimmün hastalıklar, ilaç toksisitesi, malignite gibi pek çok neden bildirilmektedir. SS nadiren ülseratif kolitin ekstraintestinal tutulum bulgusu olarak görülebilmektedir. 2 Bu makalede, ülseratif kolit seyri sırasında SS gelişen bir olgu sunulmuş ve literatür eşliğinde tartışılmıştır. OLGU SUNUMUÜlseratif kolit tanısıyla takip ve tedavi edilen 14 yaşında erkek hasta steroid azaltma periyodunda oral prednizolon (20 mg/gün), mesalazin (60 mg/kg/gün) ve azatioprin (AZT) (1,4 mg/kg/gün) almaktayken, çocuk acil servisine yüksek ateş ve son günlerde oluşan tüm ekstremitelerde bulunan ağrılı eritematöz lezyonlar nedeniyle getirildi. Hastanın başvuru sırasında ishal ya da kanlı dışkılama şikâyeti bulunmamak-

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“…We describe a 12‐month‐old male diagnosed with SS based on two major criteria (abrupt onset of the typical rash and histopathologic confirmation) and four minor criteria (prior vaccination, fever, leukocytosis, and response to treatment) 2 …”

Section: Discussionmentioning

confidence: 99%

“…We describe a 12-month-old male diagnosed with SS based on two major criteria (abrupt onset of the typical rash and histopathologic confirmation) and four minor criteria (prior vaccination, fever, leukocytosis, and response to treatment). 2 A febrile reaction, resulting from adaptive immunity stimulation, is a well-known adverse reaction to live attenuated vaccines, such as MMRV. 3,4 A significantly higher level of granulocyte colony-stimulating factor (G-CSF) was noted in recipients with febrile illness within 48 h of vaccination, particularly in combination with two or three vaccines.…”

Section: Discussionmentioning

confidence: 99%