Sweet Syndrome in Pediatric Active Ulcerative Colitis

Miranda, Estefanía; Meza, Rodrigo; Kolbach, Marianne; Torres, Javiera; Harris, Paul

doi:10.14309/ajg.0000000000000645

Cited by 3 publications

(2 citation statements)

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“…SS usually presents in individuals in their sixth decade of life [7,10,11]. Occurrence of SS in the pediatric population is rare (with an estimated 5-8% of cases of SS being reported in children [12]), although several cases of pediatric SS have been recently reported in literature [13][14][15][16][17][18][19][20]. In a 2019 French study of 10 pediatric SS patients, the investigators reported a median age of 2.7 years at presentation and a female to male ratio of 2:3.…”

Section: Key Pointsmentioning

confidence: 99%

New Practical Aspects of Sweet Syndrome

et al. 2022

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Sweet syndrome (SS), or acute febrile neutrophilic dermatosis, is an inflammatory, non-infectious skin reaction characterized clinically by tender, erythematous papules/plaques/pustules/nodules commonly appearing on the upper limbs, trunk, and head and neck; histologically, SS is characterized by dense neutrophilic infiltrate in the dermis. SS is accompanied by fever; an elevation of inflammatory markers (e.g., erythrocyte sedimentation rate, C reactive protein) in serum may also be observed. Although most cases of SS are idiopathic, SS also occurs in the setting of malignancy or following administration of an associated drug. SS has also been reported in association with pregnancy and a burgeoning list of infectious (most commonly upper respiratory tract infections) and inflammatory diseases; likewise, the litany of possible iatrogenic triggers has also grown. Over the past several years, a wider spectrum of SS presentation has been realized, with several reports highlighting novel clinical and histological variants. Corticosteroids continue to be efficacious first-line therapy for the majority of patients with SS, although novel steroid-sparing agents have been recently added to the therapeutic armamentarium against refractory SS. New mechanisms of SS induction have also been recognized, although the precise etiology of SS still remains elusive. Here, we catalogue the various clinical and histological presentations of SS, summarize recently reported disease associations and iatrogenic triggers, and review treatment options. We also attempt to frame the findings of this review in the context of established and emerging paradigms of SS pathogenesis.

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Section: Key Pointsmentioning

confidence: 99%

New Practical Aspects of Sweet Syndrome

et al. 2022

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“…7 Literatürde SS gelişen çocuk hastalar da bildirilmiştir. 5,[8][9][10] Hastamızın klinik ve histopatolojik bulguları SS tanı kriterlerinin tamamını karşılamaktaydı.…”

Section: Discussionunclassified

Sweet Syndrome in a Pediatric Patient with Ulcerative Colitis

BAŞARAN,

BOTSALI,

ARSLAN

et al. 2024

Turkiye Klinikleri J Pediatr

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Akut ateşli nötrofilik dermatoz olarak da bilinen Sweet sendromu (SS) hassas eritematöz plaklar veya nodüller, ateş, artralji, oftalmolojik belirtiler, baş ağrısı, oral veya genital lezyonlarla seyreden nadir bir hastalıktır. 1 Etiyolojisinde inflamatuar, otoimmün hastalıklar, ilaç toksisitesi, malignite gibi pek çok neden bildirilmektedir. SS nadiren ülseratif kolitin ekstraintestinal tutulum bulgusu olarak görülebilmektedir. 2 Bu makalede, ülseratif kolit seyri sırasında SS gelişen bir olgu sunulmuş ve literatür eşliğinde tartışılmıştır. OLGU SUNUMUÜlseratif kolit tanısıyla takip ve tedavi edilen 14 yaşında erkek hasta steroid azaltma periyodunda oral prednizolon (20 mg/gün), mesalazin (60 mg/kg/gün) ve azatioprin (AZT) (1,4 mg/kg/gün) almaktayken, çocuk acil servisine yüksek ateş ve son günlerde oluşan tüm ekstremitelerde bulunan ağrılı eritematöz lezyonlar nedeniyle getirildi. Hastanın başvuru sırasında ishal ya da kanlı dışkılama şikâyeti bulunmamak-

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Ulcerative Colitis Concomitant with Cytomegalovirus Infection, Bullous Sweet’s Syndrome, and Acute Myeloid Leukemia: A Case Report and Literature Review

Zhu,

Hu,

et al. 2023

JIR

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Sweet Syndrome in Pediatric Active Ulcerative Colitis

Cited by 3 publications

References 0 publications

New Practical Aspects of Sweet Syndrome

New Practical Aspects of Sweet Syndrome

Sweet Syndrome in a Pediatric Patient with Ulcerative Colitis

Ulcerative Colitis Concomitant with Cytomegalovirus Infection, Bullous Sweet’s Syndrome, and Acute Myeloid Leukemia: A Case Report and Literature Review

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