Sweet syndrome in early childhood

Abstract

A 21-month-old child with acute febrile dermatosis, leukocytosis and skin biopsy showing intradermal neutrophil infiltrate was diagnosed as suffering from Sweet syndrome. This syndrome is rare in children, described heretofore in only seven paediatric patients. The clinical and histological features, differential diagnosis, as well as the potential association with more widespread systemic diseases are discussed.

Pediatric Sweet syndrome. A retrospective study

“…3 The lesions may appear on areas of trauma 8 and can have pseudovesiculation or pathergy. 12 The differential diagnosis of SS should be made with urticaria, urticarial vasculitis, acute hemorrhagic edema of infancy, Henoch-Sch€ onlein purpura, erythema multiforme, cellulitis, granuloma faciale, erythema elevatum diutinum, bowel bypass-related dermatosis, pyoderma gangrenosum, and drug hypersensitivity reactions. Infection should always be ruled out.…”

Pediatric Sweet Syndrome: Case Report and Literature Review

“…References from identified papers were also searched. We have identified 66 reported cases in the literature, including this case report (2,3,6–59).…”

Acute febrile neutrophilic dermatosis (Sweet’s syndrome) in childhood and adolescence: two new patients and review of the literature on associated diseases

“…Twentyseven (42%) patients were categorized in the group "classic/idiopathic Sweet's syndrome". Thirteen (21%) of these presented without associated diseases (detailed data not shown [3,6,19,20,24,25,32,34,51,53,59]) and 14 patients (22%) were reported with transient diseases, mostly respiratory tract infections or otitis media [12,13,15,26,27,29,36,39,41,44,47,55]. These patients were not included in the detailed analysis and are not shown in Tables 2 and 3.…”