Sweet’s Syndrome Induced by Oral Contraceptive

Sáez, Miguel; García‐Bustínduy, M.; Noda, Antonio Sedeño; Guimerá, Francisco; Dorta, S.; Escoda, M.; Fagundo, E.; Sánchez, Rosalba; Martín‐Herrera, Antonio; Montelongo, Rafael García

doi:10.1159/000051820

Cited by 20 publications

(8 citation statements)

References 5 publications

(6 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Sweet's syndrome has also been linked to the oral contraceptive pill. 6 The association that we found with the Mirena IUS adds weight to this hypothesis. It also serves to highlight the importance of detailed clinical history taking in patients with dermatological signs, particularly with regard to hormonal contraception and implants/prostheses.…”

Section: Case Reportmentioning

confidence: 52%

Sweet's syndrome and a Mirena<SUP>®</SUP> intrauterine system

Hamill

Bowling²,

Vega-Lopez³

2004

j fam plann reprod health care

View full text Add to dashboard Cite

show abstract

Section: Case Reportmentioning

confidence: 52%

Sweet's syndrome and a Mirena<SUP>®</SUP> intrauterine system

Hamill

Bowling²,

Vega-Lopez³

2004

j fam plann reprod health care

View full text Add to dashboard Cite

show abstract

“…The implicated medications were trimethoprim–sulphamethoxazole 1,2 (two subjects), ethinyl oestradiol and levonorgestrel 3 (one subject), minocycline 4 (two subjects), all‐ trans ‐retinoic acid 5 (seven subjects), granulocyte colony‐stimulating factor 6 (30 subjects), hydralazine 7 (two subjects), diclofenac 8 (one subject), carbamazepine 9 (one subject) and nitrofurantoin 10 (one subject). In addition we reported the first known case of diazepam‐induced Sweet's syndrome 11 and the second case of Sweet's syndrome associated with an oral contraceptive containing ethinyl oestradiol and gestodene 12 . The age of the subjects with drug‐induced Sweet's syndrome ranged from 5 to 75 years (mean age, 47 years), and the majority were women (32 of 49).…”

mentioning

confidence: 98%

Drug‐induced Sweet's syndrome

Sáez

García‐Bustínduy

Noda

et al. 2004

Acad Dermatol Venereol

View full text Add to dashboard Cite

Laugier-Hunziker syndrome (LHS) is a rare disorder characterized by melanotic pigmentation of the mouth and lips which is frequently associated with longitudinal melanonychia. Laugier and Hunziker described lenticular melanotic pigmentation of the oral cavity and lips in 1970. 1 Some cases have been described in which the neck, thorax, abdomen, fingers and soles have been involved. Fingernails are more frequently involved than the toenails. 2 Melanonychia may also be seen with or after lichen planus (LP). 3,4 We report a case of LHS associated with actinic LP.A 37-year-old Turkish woman was referred to our clinic with melanotic macules on the face, a pruritic annular plaque on the malar area of her face and hyperpigmented streaks on her nails, which had appeared for 19 years, 10 months and 6 years, respectively.Examination revealed the patient's pigmented macules on the lips, gums, buccal mucosa and midline of the hard palate ( fig. 1a). There were melasma and pinkish annular plaque, with a hyperpigmented centre ( fig. 1b). There were longitudinal melanonychia on her fingernails ( fig. 1c) and toenails. Hyperpigmented slate-grey to brown macular lesions were seen over her back. Examination of intertriginous areas did not reveal any evidence of acanthosis nigiricans. The skin phototype according to Fitzpatrick's scale was IV.Results of routine laboratory tests were within normal ranges, including triiodothyronine (T3), thyroxine (T4) and thyrotropin (TSH). The patient had smoked for 20 years. Her mother had melasma. Histopathological examination of pigmented macula on the buccal mucosa showed an accumulation of melanin in the cells of the basal layer of the acanthotic epidermis and an increased number of melanophages in the upper dermis ( fig. 2). Histopathologically, there was thinning of the epidermis with vacuolar alteration of the basal layer, an artifactural cleft between the epidermis and the lichenoid infiltrate and pigment incontinence in the upper dermis on the annular lesion over the cheek (fig. 3).Since the first description by Laugier and Hunziker, many cases of LHS have been reported. 2,[5][6][7] In this syndrome, the essential lesions are manifested as lenticular-pigmented macules, which have different colours (from grey to brown to blueblack) and a smooth surface. Generally symptoms are absent. The most common sites are the lips (especially the lower lip) and the oral cavity (buccal mucosa and hard palate). Other sites such as labial comissure, the gums the floor of the mouth and the tongue are less frequent. Other locations such as the abdomen and the fingers have been involved. Fingernail involvement can present as a single longitudinal 1-2-mm-wide streak or as a double 2-3-mm-wide longitudinal streak on the lateral parts of the nail plate, as a homogeneous pigmentation of the radial or ulnar half of the nail, and complete pigmentation of the nail. All four types of nail involvement may simultaneously involve one or more nails of the fingers and /or toes. 2 fig. 1 (a) Multiple pigmented macules lo...

show abstract

“…On the other hand, the pregnant woman presents progressive neutrophilia during gestation which leads to a situation of major inflammation facilitating the work [2]. The role of hormonal factors could also be raised because of the induction of neutrophilic dermatoses such as Sweet's syndrome by oral contraceptives or their occurrence during pregnancy [15]. The treatment of the PSPG is not unique and is identical to that of the PG occurring de novo.…”

Section: Discussionmentioning

confidence: 99%

Post-Partum Pyoderma Gangenosum Following a Cesarean Section

Diallo¹,

Diop²,

Ba³

et al. 2017

Dermatol Case Rep

View full text Add to dashboard Cite

The occurrence of Pyoderma gangrenosum (PG) during pregnancy or postpartum has rarely been reported. These forms can also occur on a recent scar facilitated by the pathergy phenomenon. A 25-year-old woman showed an abruptly worsening of a post-caesarean wound that evolved rapidly into a painful, purulent, extensive ulcer with breakdown of sutures, along with fever and leukocytosis despite antibiotic therapy. The diagnosis of postoperative PG was evoked on the unusual course of the surgical wound, the existence of old cribriform scars on the legs, the clinical appearance of the ulceration around the surgical incision and confirmed by histology, as well as the favourable outcome under systemic corticosteroid. This case raises once again the issue of the possible relationship between pregnancy and PG. In our case, pregnancy could have triggered the PG, and the Caesarean section facilitated its clinical expression by the pathergy phenomenon. Thus, pregnancy could be in the same way as chronic inflammatory diseases, such as arthritis, inflammatory bowel disease and haematological disorders, a triggering or exacerbating factor of PG.

show abstract

Sweet’s Syndrome Induced by Oral Contraceptive

Cited by 20 publications

References 5 publications

Sweet's syndrome and a Mirena<SUP>®</SUP> intrauterine system

Sweet's syndrome and a Mirena<SUP>®</SUP> intrauterine system

Drug‐induced Sweet's syndrome

Post-Partum Pyoderma Gangenosum Following a Cesarean Section

Contact Info

Product

Resources

About