Sweet's syndrome as a complication of radiotherapy for squamous carcinoma of the pharynx

Localized Sweet's Syndrome in an Irradiated Field

“…We suggest that the radiotherapy induced cell damage and consequently a decreased threshold to the stimuli may have induced Sweet's syndrome to localize to the irradiated area. Further, the skin lesions in our patient extended to the untreated skin of the right lower extremity, which may be explained by a microcirculatory phenomenon 4 .…”

“…In most patients, Sweet's syndrome developed in the irradiated field during the course of radiotherapy and spread to non-irradiated fields (cases 1, 2, 3, and 5) [2][3][4][5] . Therefore, we could not exclude malignancies and radiation as triggering factors in the development of skin lesions.…”

“…A few cases of Sweet's syndrome in the literature have been associated with radiotherapy, but most of those patients had malignancies with signs of recurrence or developed in the skin lesion during the course of radiotherapy [2][3][4][5] . Only one case presented with skin lesions of Sweet's syndrome that corresponded with the irradiated area 1 year previously without recurrence of the cancer 6 .…”

A Case of Sweet's Panniculitis Associated with Spinal Metastasis from Prostate Cancer

“…In addition, the site of the patient's skin lesions (arms and trunk) were not associated with the site of pelvic radiation. In several previously reported cases of Sweet's syndrome associated with radiotherapy, skin lesions were principally localized around the site of radiotherapy [12][13][14][15] .…”

Sweet's syndrome in prostate cancer

“…Radiotherapy has been associated with SS in case reports of patients undergoing treatment for breast and oropharyngeal tumours. [9][10][11] In each of these cases, the cutaneous manifestations were located principally within the radiotherapy field extending to the surrounding untreated skin. In our case, there was little skin toxicity, and the rash originated and was most severe outside the treatment fields.…”