Sweet Bell Pepper: A Focus on Its Nutritional Qualities and Illness-Alleviated Properties

Younes, Areej Hazem; Mustafa, Yasser Fakri

doi:10.1007/s12291-023-01165-w

Cited by 5 publications

(2 citation statements)

References 106 publications

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“…[35] However, the ripeness, developing atmosphere, fertilizers, and conditions of preservation all affect these GSBP-related medicinal actions. [36,37] On the other hand, little research has been done on the preserved seeds' internal fruit-derived compounds and biologically significant characteristics, in contrast to the edible portion of GSBP (38,39). The fact that GSBP seeds are one of the most biowasteful and are routinely disposed of by restaurants is another source of disappointment.…”

Section: Introductionmentioning

confidence: 99%

Unveiling the Biomedical Applications of Novel Coumarins Isolated From Capsicum Annuum L. Seeds by a Multivariate Extraction Technique

Younes,

Mustafa

2024

Chemistry & Biodiversity

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For the first time, kinetic thermomagnetic extraction is a novel approach presented in this work. It required the application of four distinct variables: rotation speed (50, 75, and 100 rpm), magnetic field (0.8, 1.2, and 1.6 T), time interval (30, 60, and 90 min), and temperature (45, 55, and 65°C). Numerous phytochemical categories were detected in the 81 crude chloroform extracts of green sweet bell pepper seeds that were collected, according to phytochemical analysis. Nine extracts were discovered to be linked to the coumarin chemical class and to have the same two extraction parameters: a 90‐minute extraction duration and a 55°C extraction temperature. To enable their coumarin contents to be chemically separated and chromatographically purified, two of these extracts containing coumarin were chosen. Four new phytocoumarins have been identified and their molecular structures distinguished using FTIR spectra, 1H‐NMR, 13C‐NMR, and mass analysis. The results demonstrated that the extracted phytocoumarins have exceptional oxidative stress‐mitigating characteristics, ranging from 71.51 to 81.48%, when compared to a positive control. Furthermore, they showed excellent cytotoxicity against the test malignant populations (IC50 values of 46.76–81.45 μg/ml). The isolates need to be taken into account as dual COX‐2/5‐LOX antagonists because they also showed a selective anti‐inflammatory effect

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Section: Introductionmentioning

confidence: 99%

Unveiling the Biomedical Applications of Novel Coumarins Isolated From Capsicum Annuum L. Seeds by a Multivariate Extraction Technique

Younes,

Mustafa

2024

Chemistry & Biodiversity

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“…NPs or their derivatives are frequently utilized as drugs to treat a variety of diseases, including diabetes, cardiovascular disorders, cancer, and others. [4,5] Numerous kinds of bioactive chemical compounds are synthesized by various plants; [6,7] as shown in Figure 1, most of them don't seem to have a direct role in development or growth; they are usually known as secondary metabolites (SM). [8] These compounds frequently spread widely in specific classifications within the kingdom of plants.…”

Section: Introduction 1natural Productsmentioning

confidence: 99%

Plant‐Derived Coumarins: A Narrative Review of Their Structural and Biomedical Diversity

Younes,

Mustafa

2024

Chemistry & Biodiversity

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Plant‐derived coumarin (PDC) is a naturally occurring heterocyclic backbone that belongs to the benzopyrone family. PDC and its based products are characterized by low toxicity and high distribution in a variety of herbal treatments that have numerous therapeutic potentials. These include anticoagulants, antibacterials, anti‐inflammatory agents, anticancer agents, antioxidants, and others. So, it may be appropriate to investigate the qualities and potential bioactivities of PDCs. This article provides an overview of the biomedical potentials, availability, and clinical use possibilities of PDCs, with a focus on their important modes of action, using information on various pharmacological qualities discovered. The data used in this study came from published research between 2015 and 2023. We reviewed a selection of databases, including PubMed, Scopus, Web of Science, and Google Scholar, during that period. In conclusion, because of their abundance in medicinal plants, the clinical biochemistry attributes of PDCs are currently of interest. In a variety of medical specialties, PDCs serve a useful role as therapeutic agents.

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Novel coumarins from green sweet bell pepper seeds: Their isolation, characterization, oxidative stress-mitigating, anticancer, anti-inflammatory, and antidiabetic properties

Younes,

Mustafa

2024

Journal of Molecular Structure

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Sweet Bell Pepper: A Focus on Its Nutritional Qualities and Illness-Alleviated Properties

Cited by 5 publications

References 106 publications

Unveiling the Biomedical Applications of Novel Coumarins Isolated From Capsicum Annuum L. Seeds by a Multivariate Extraction Technique

Unveiling the Biomedical Applications of Novel Coumarins Isolated From Capsicum Annuum L. Seeds by a Multivariate Extraction Technique

Plant‐Derived Coumarins: A Narrative Review of Their Structural and Biomedical Diversity

Novel coumarins from green sweet bell pepper seeds: Their isolation, characterization, oxidative stress-mitigating, anticancer, anti-inflammatory, and antidiabetic properties

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