Swallowing dysfunction related to obstructive sleep apnea: a nasal fibroscopy pilot study

Valbuza, Juliana Spelta; Oliveira, Márcio Moysés de; Zancanella, Edilson; Conti, Cristiane Fiquene; Prado, Lucila Bizari Fernandes do; Carvalho, Luciane Bizari Coin de; Prado, Gilmar Fernandes do

doi:10.1007/s11325-010-0474-9

Cited by 55 publications

(39 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It has been previously shown that individuals with OSA aspirate a larger volume of oral secretions while sleeping as compared with control subjects (26). Additionally, one study showed evidence of a higher rate of subclinical swallowing dysfunction in individuals with OSA, believed to be secondary to neuromuscular injury caused by snoring (27). Alternatively, the positive pressure ventilation itself may lead to aspiration.…”

Section: Original Researchmentioning

confidence: 99%

The Spectrum of Lung Disease due to Chronic Occult Aspiration

Cardasis¹,

MacMahon²,

Husain

2014

Annals ATS

View full text Add to dashboard Cite

show abstract

Section: Original Researchmentioning

confidence: 99%

The Spectrum of Lung Disease due to Chronic Occult Aspiration

Cardasis¹,

MacMahon²,

Husain

2014

Annals ATS

View full text Add to dashboard Cite

show abstract

“…A greater bolus volume is required to elicit the swallowing reflex, swallowing onset latency is delayed, and bolus leakage throughout the pharynx occurs more frequently in OSA patients and snorers compared to controls (Zohar et al, 1998a; Teramoto et al, 1999; Jäghagen et al, 2000; Levring Jaghagen et al, 2003; Valbuza et al, 2011b). Inhibition of inspiration associated with swallowing is also less pronounced in OSA (Teramoto et al, 1999).…”

Section: Functionmentioning

confidence: 99%

Functional Role of Neural Injury in Obstructive Sleep Apnea

Saboisky¹,

Butler²,

Gandevia³

et al. 2012

Front. Neur.

View full text Add to dashboard Cite

The causes of obstructive sleep apnea (OSA) are multifactorial. Neural injury affecting the upper airway muscles due to repetitive exposure to intermittent hypoxia and/or mechanical strain resulting from snoring and recurrent upper airway closure have been proposed to contribute to OSA disease progression. Multiple studies have demonstrated altered sensory and motor function in patients with OSA using a variety of neurophysiological and histological approaches. However, the extent to which the alterations contribute to impairments in upper airway muscle function, and thus OSA disease progression, remains uncertain. This brief review, primarily focused on data in humans, summarizes: (1) the evidence for upper airway sensorimotor injury in OSA and (2) current understanding of how these changes affect upper airway function and their potential to change OSA progression. Some unresolved questions including possible treatment targets are noted.

show abstract

“…These alterations can be symptomatic or asymptomatic and consist mostly of premature bolus leakage (from the oral cavity into the pharynx) and food residue in the pharynx after swallowing. 9,10,13,14 Pharyngoesophageal manometry assesses the compressive muscle force of the pharyngeal and esophageal muscles during swallowing, aiding in the understanding of the physiopathology of oropharyngeal dysphagia. 15---17 Hypothetically, neurological and muscular disorders of the upper airways associated with OSA 18 can impair the force and dynamics of pharyngoesophageal contractions during swallowing, contributing to the dysphagia observed in many cases of OSA.…”

Section: Introductionmentioning

confidence: 99%