Swallowing Dysfunction and Quality of Life in Adults With Surgically Corrected Esophageal Atresia/Tracheoesophageal Fistula as Infants

Gibreel, Waleed; Zendejas, Benjamin; Antiel, Ryan M.; Fasen, Geoffrey; Moir, Christopher R.; Zarroug, Abdalla E.

doi:10.1097/sla.0000000000001978

Cited by 30 publications

(26 citation statements)

References 23 publications

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“…How transition is managed in the future is an important issue for OA care and other chronic paediatric conditions, as the population of long term survivors continues to increase. International studies such as this alongside work from Australia [22], Finland [9,10] Holland [23,24] and more recently the USA [25] are key in highlighting the need for careful planning of patient centred transitional and adult care. This may include the need for some stratification of transition and follow up.…”

Section: Discussionmentioning

confidence: 99%

A patient led, international study of long term outcomes of esophageal atresia: EAT 1

Svoboda¹,

Fruithof²,

Widenmann-Grolig³

et al. 2018

Journal of Pediatric Surgery

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Section: Discussionmentioning

confidence: 99%

A patient led, international study of long term outcomes of esophageal atresia: EAT 1

Svoboda¹,

Fruithof²,

Widenmann-Grolig³

et al. 2018

Journal of Pediatric Surgery

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“…[117] The prevalence of swallowing dysfunction in adults was reported to be 82% in one study that followed 97 EA patients 18-63 years following surgical repair. [98] GERD and esophageal strictures were present in some, but not all of these patients. Other reasons for dysphagia include abnormal esophageal motility, colonic interposition leading to stasis of food in the neo-esophagus, and ongoing esophageal strictures or narrowing.…”

Section: Long Term Follow Upmentioning

confidence: 95%

“…[6, 98] When evaluating a patient, structural and inflammatory causes should be excluded first. There are pros and cons to each testing modality (Table 2).…”

Section: Dysphagiamentioning

confidence: 99%

How to Care for Patients with EA-TEF: The Known and the Unknown

Mousa

Krishnan

Hassan

et al. 2017

Curr Gastroenterol Rep

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EA patients are at high risk for gastroesophageal reflux and esophageal strictures, and the sequela that result. Extraintestinal manifestations of gastroesophageal reflux disease (GERD) can appear similar to other pathologic diagnoses commonly found in EA patients, such as congenital stricture, eosinophilic esophagitis, esophageal dysmotility, tracheomalacia, recurrent fistula, aspiration, etc. Therefore, it is important to have a standardized way to monitor for these issues. pH impedance allows for detection of nonacid reflux and the height of reflux, which are important in correlating symptoms with reflux episodes. A multidisciplinary approach is beneficial in evaluating and monitoring EA patients in the long term.

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“…The remaining two articles described HRQoL among adults with EA only. 39,40 Two articles described HRQoL in patients with EA recruited from the USA 33,39 and three articles described patients resident in Asian countries. 25,28,34 Moreover, six articles (41%) reported on HRQoL in international samples, in five of which HRQoL in Swedish-German pediatric EA cohorts was described.…”

Section: Current Literature Regarding Hrqol In Patients Following Ea mentioning

confidence: 99%

“…[41][42][43][44][45] Others were symptom-specific, focusing on swallowing or on the gastrointestinal tract. 39,[46][47][48][49] Three questionnaires were regarded as condition-specific, 24,26,28,30,32 two of which were lacking reports on validity and reliability. 28,32 ►Table 2 lists the seven HRQoL questionnaires with demonstrated validity and reliability.…”

Section: Current Literature Regarding Hrqol In Patients Following Ea mentioning

confidence: 99%

Health-Related Quality of Life in Patients after Repair of Esophageal Atresia: A Review of Current Literature

2020

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Patients born with esophageal atresia (EA) require advanced reconstructive surgery and risk long-term digestive and respiratory morbidity. We describe the state of current literature on these patients' health-related quality of life (HRQoL) and give recommendations for future research. A literature search was conducted in PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and PsychINFO and included articles from 2015 to December 28, 2019. Criteria for selecting articles were predefined. Seventeen articles describing HRQoL among children, adolescents, and adults were found, two of which focused on adults only. Six studies included international samples and among 15 quantitative studies sample sizes varied from 17 to 928 (median: 46). Seven different HRQoL questionnaires were used for children, three of which were specially adjusted for EA, of which one was reported validity and reliability. Four questionnaires were used for adults, one of which was generic and three symptom-specific, referring to swallowing or to the gastrointestinal tract. Hence, HRQoL outcomes were described differently. However, several studies of pediatric patients with EA revealed associations between lower HRQoL and particular congenital and surgical characteristics, which reflected disease severity. In two out of three articles, pediatric patients with EA had lower overall scores than healthy children. Digestive symptoms consistently lowered HRQoL scores in children and adults. Prior to 2015, only 12 studies were published, which illustrate a recent expansion in this field. Various HRQoL aspects and heterogeneous samples are examined, and outcomes differently reported. Current literature suggests that clinical subgroups of children with EA present with impaired HRQoL and that digestive symptomology influence HRQoL negatively. Conclusions of studies focusing on adults with EA are difficult to draw. Additional research is required.

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Swallowing Dysfunction and Quality of Life in Adults With Surgically Corrected Esophageal Atresia/Tracheoesophageal Fistula as Infants

Abstract: Swallowing dysfunction is common in adults who underwent EA/TEF repair as infants; however, patients reported minimal effect on QOL or day-to-day activities. The SDQ is a valid and reliable tool to measure the full spectrum of swallowing dysfunction in the EA/TEF repair population.

Cited by 30 publications

References 23 publications

A patient led, international study of long term outcomes of esophageal atresia: EAT 1

A patient led, international study of long term outcomes of esophageal atresia: EAT 1

How to Care for Patients with EA-TEF: The Known and the Unknown

Health-Related Quality of Life in Patients after Repair of Esophageal Atresia: A Review of Current Literature

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