Sutures, ligatures and staples

Patel, Kirtikbhai A; Thomas, WEG

doi:10.1383/surg.23.2.56.60344

Cited by 9 publications

(14 citation statements)

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“…They are either multifilaments (twisted or braided) or monofilament. 2 They have physical and chemical properties quite different from each other. In the last century, synthetic materials, both absorbable and non-absorbable, have been introduced in the making of surgical sutures.…”

Section: Introductionmentioning

confidence: 99%

Development and characterization of antibacterial braided polyamide suture coated with chitosan-citric acid biopolymer

et al. 2017

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Braided polyamide sutures are frequently used in dermatologic surgery for wound closure. However, braided sutures promote bacteria proliferation. In order to prevent wound complications due to this effect, antibacterial sutures should be used. The main objective of this study is the development of new non-absorbable antibacterial polyamide braided suture. This paper suggests new coating process that leads to obtain suture uniformly covered by antibacterial film enclosing chitosan, which is known for its antibacterial benefit. Mechanical properties and surface morphology of developed sutures were investigated by using mechanical tests. Sutures surfaces were also examined by scanning electron microscope, to perceive spreading of coating product on suture surface. In order to identify potential reactions between chemical compounds present in coating solution and suture material, sutures were analyzed by ATR-IF spectroscopy. It has been demonstrated that many eventual bonds between compounds present in coating solutions and polyamide macromolecular chain may occur. The existence of these bonds implies the fixation of biopolymer coating on suture surface. It has been demonstrated that uniform surface may be obtained by progressively applying coating solution containing little amount of chitosan on suture surface. We have also found that developed coating process has not affected mechanical properties of suture, which still meet United States Pharmacopeia requirement. Finally, antibacterial effects against four colonies, very widespread in hospitals, were studied. Prominent antibacterial effects of braided polyamide suture against two gram-positive ( S Aureus, S epidermidis) and two gram-negative ( E coli and P aeruginosa) colonies are presented. Optimal result of best properties is obtained by applying three layers of biopolymer coating comprising 1% chitosan and 10% citric acid. The new developed suture coating process appears as a promising method for obtaining important antibacterial effect with smooth suture surface.

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Section: Introductionmentioning

confidence: 99%

Development and characterization of antibacterial braided polyamide suture coated with chitosan-citric acid biopolymer

et al. 2017

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“…In this study, blending process aimed at obtaining a composition with desirable properties to fabricate absorbable sutures; therefore, the final blend should have a proper strain to better control and handle the resulting sutures. On the other hand, strength is a significant factor in the preparation of sutures with desirable properties [1,17]. The main point was to find a composition with the maximum elongation against the lowest strength reduction.…”

Section: Tensile Testmentioning

confidence: 99%

Investigation on the Mechanical, Thermal, Bio-Degradation, and Bio-Compatibility Properties of Poly (Lactic Acid) / Poly (Ethylene Glycol) Blend

Zarinkolah

Bagheri

Hosseinkhani

et al. 2021

IIUMEJ

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Absorbable sutures are widely used in surgery. In addition to acceptable mechanical properties, the surgical sutures should exhibit favorable degradability properties. In this research, the mechanical and thermal properties, hydrophilicity, biodegradability, pH changes, and drug release profile of polylactic acid (PLA) and polyethylene glycol (PEG) alloy were examined to fabricate absorbable sutures. The test results for the mechanical properties showed that the strength of the PLA/PEG alloy decreased with increasing PEG content, leading to an increase in elongation. The differential thermal analysis indicated that the resulting material was above its glass transition temperature (Tg) at ambient temperature and was thus flexible enough. According to the degradation test results, the alloys were degraded similar to the commercial sample. Furthermore, the pH measurements revealed that the degradation of the alloy had no significant effect on the pH of the environment. Bupivacaine hydrochloride was incorporated into a certain amount of PLA and PEG, and the drug release rate was then measured. The sample provided a suitable substrate for burst release. Moreover, the cytotoxicity test was carried out to evaluate the biocompatibility properties of the PLA/PEG alloy and it was found that this alloy is biocompatible and the biocompatibility of the material decreases with increasing drug loading. ABSTRAK: Sutur boleh serap telah digunakan dalam pembedahan secara meluas. Tambahan kepada sifat-sifat mekanikal ini, sutur pembedahan perlu memiliki ciri-ciri kebolehurain yang dikehendaki. Dalam kajian ini, sifat-sifat mekanikal dan terma, kehidrofilikan, kebolehuraian, perubahan pH, dan profil penguraian ubat asid polilaktik (PLA) dan aloi polietilena glikol (PEG) telah dikaji bagi mencipta sutur boleh serap. Hasil kajian mendapati sifat-sifat mekanikal menunjukkan kekuatan PLA/PEG aloi berkurangan dengan penambahan level PEG, menyebabkan bertambahnya pemanjangan. Analisis pembezaan terma menunjukkan hasil bahan adalah melepasi suhu perubahan gelas (Tg) pada suhu sekitar dan oleh itu sangat lentur. Berdasarkan hasil kajian degradasi, aloi ini telah digradasi seperti sampel komersial. Tambahan lagi, ukuran pH menunjukkan degradasi aloi ini tidak menunjukkan kesan langsung pada pH persekitaran. Bupivacaine hidroklorida dimasukkan ke dalam PLA dan PEG, dan kadar ubat dibebaskan kemudiannya diukur. Sampel substrat yang bersesuian disediakan bagi pelepas letus. Tambahan, ujian Kesitotoksikan telah dijalankan bagi menilai ciri-ciri keserasian-bio aloi PLA/PEG dan didapati aloi ini serasi-bio dan keserasian-bio bahan berkurangan dengan penambahan beban ubat.

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“…There must be a proper match between the suture strength and the tissue strength. 24 To investigate the breaking strength, breaking elongation, knot strength, knot-pull strength, and strength with needle of DAC suture (USP 2-0), Universal Testing Instruments AGS-X (Shimadzu, Japan) was performed at a testing speed of 5.0 mm/s. VicrylV R Plus suture (USP 2-0), a multifilament braided PLGA suture impregnated with triclosan to provide antimicrobial protection, was employed as control.…”

Section: Mechanical Properties Of Dac Suturementioning

confidence: 99%

Fabrication and feasibility study of an absorbable diacetyl chitin surgical suture for wound healing

et al. 2015

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Diacetyl chitin (DAC) is an acidylated chitin obtained using acetic anhydride mixed perchloric acid system. By wet spinning and weaving technique, DAC has been successfully developed into a novel absorbable surgical suture. Thanks to the unique properties of chitins, the potential application of this novel monocomponent multifilament DAC suture may break the monopoly of synthetic polymer sutures in wound closure area. In this study, DAC was synthesized and characterized by multiple approaches including elemental analysis, Fourier transform infrared spectrometry (FTIR), and X-ray diffraction (XRD). In addition, we performed the feasibility assessment of DAC suture (USP 2-0) as absorbable suture for wound healing. Several lines of evidences suggested that DAC suture had comparable mechanical properties as synthetic polymer sutures. Moreover, DAC suture retained approximately 63% of the original strength at 14 days and completely absorbed in 42 days with no remarkable tissue reaction in vivo. Most important of all, DAC suture significantly promoted skin regeneration with faster tissue reconstruction and higher wound breaking strength on a linear incisional wound model. All these results demonstrated the potential use of DAC suture in short- or middle-term wound healing, such as epithelial and connective tissue.

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Sutures, ligatures and staples

Cited by 9 publications

References 0 publications

Development and characterization of antibacterial braided polyamide suture coated with chitosan-citric acid biopolymer

Development and characterization of antibacterial braided polyamide suture coated with chitosan-citric acid biopolymer

Investigation on the Mechanical, Thermal, Bio-Degradation, and Bio-Compatibility Properties of Poly (Lactic Acid) / Poly (Ethylene Glycol) Blend

Fabrication and feasibility study of an absorbable diacetyl chitin surgical suture for wound healing

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