Suture Granuloma Showing False-Positive Findings on FDG-PET

Abstract

We report a case of a 33-year-old male with a mixed germ-cell testicular tumor. Postoperative follow-up FDG-PET revealed concentration of FDG in the left inguinal area which is not tumor metastasis or local recurrence but suture reactivity granuloma. In this paper, we reviewed suture granulomas associated with false-positive findings on FDG-PET after surgery. If FDG-PET will be used more frequently in the future, it will be necessary to refrain from using silk thread in order to prevent any unnecessary surgery.

Suture Granuloma With False-Positive Findings on FDG-PET/CT Resected via Laparoscopic Surgery

“…ma'' and ''PET''), 7 cases (5 publications) of suture granulomas associated with false-positive findings on FDG-PET after surgery have been published (Table 1). [1][2][3][4][5] Six of these cases occurred after surgery for malignancy, with a time interval between the primary operation and the radiologic diagnosis of the lesion of 6 months to 15 years (median, 10 months). In only 1 case was US-guided fine-needle aspiration performed and follow-up selected in a patient with a diagnosis of suture granuloma; surgical resection was performed in the other cases.…”

“…In the literature, there are few reports of suture granulomas showing false-positive findings on PET/CT. [1][2][3][4][5] We report here a case in which it was not possible to rule out the potential for malignancy using CT or FDG-PET/CT and the lesion was confirmed to be a suture granuloma based on a pathologic examination following laparoscopic resection.…”

Intra-abdominal suture granulomas masquerading as colon carcinoma: a case report

“…[19][20][21][22] The development of a foreign body granuloma from a suture material in the abdomen is a relatively uncommon condition that most commonly occurs in response to silk and polyfilament threads which are considered to be non-absorbable materials. 7,23 These granulomas are usually encountered in patients who have undergone recent abdominal surgery. The suture material itself and the ischemia caused by tightening of the sutures can initiate an inflammatory reaction.…”

Tissue Response to Four Different Suture Materials Used to Repair Fascia Defect In Single Port Cholecystectomy Operations

“…The granuloma can develop after every operation in which a non-absorbable suture material is used. The granuloma formation can be diagnosed on clinical suspicion and radiology [20][21][22] .…”