Sustained release of matrine via salt formation with hesperetin
Yujing Zhu,
Xiaoju Shi,
Duanxiu Li
et al.
Abstract:Matrine (MAT) is a natural tetracyclo-quinolizidine alkaloid with various pharmacological activities. Due to the excessive solubility, oral administration of MAT exhibits rapid absorption, short elimination half-life, and low bioavailability. Sustained...
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.