Sustained exercise improves vertebral histomorphometry and modulates hormonal levels in rainbow trout

Deschamps, Marie‐Hélène; Labbé, Laurent; Baloche, S.; Fouchereau-Péron, Martine; Dufour, Sylvie; Sire, Jean‐Yves

doi:10.1016/j.aquaculture.2009.07.016

Cited by 35 publications

(39 citation statements)

References 69 publications

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“…Modeling therefore results in a net increase or loss of bone material, and is thus important in bone development, bone growth and bone adaptation to changing loads. 4,6,40 Many studies have concluded that fish bone responds to increased loading by the process of modeling; however, most of these were conducted using fish with cellular bones (for example, Deschamps et al, 41 Eissa et al, 42 Fiaz et al 43 and Totland et al 44 ). The few studies that have focused on acellularboned fishes have provided somewhat secondary evidence for modeling.…”

Section: Modeling: Evidence For and Implications In Acellular Bonementioning

confidence: 99%

The enigmas of bone without osteocytes

Shahar¹,

Dean²

2013

BoneKEy Reports

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One of the hallmarks of tetrapod bone is the presence of numerous cells (osteocytes) within the matrix. Osteocytes are vital components of tetrapod bone, orchestrating the processes of bone building, reshaping and repairing (modeling and remodeling), and probably also participating in calcium-phosphorus homeostasis via both the local process of osteocytic osteolysis, and systemic effect on the kidneys. Given these critical roles of osteocytes, it is thought-provoking that the entire skeleton of many fishes consists of bone material that does not contain osteocytes. This raises the intriguing question of how the skeleton of these animals accomplishes the various essential functions attributed to osteocytes in other vertebrates, and raises the possibility that in acellular bone some of these functions are either accomplished by non-osteocytic routes or not necessary at all. In this review, we outline evidence for and against the fact that primary functions normally ascribed to osteocytes, such as mechanosensation, regulation of osteoblast/clast activity and mineral metabolism, also occur in fish bone devoid of these cells, and therefore must be carried out through alternative and perhaps ancient pathways. To enable meaningful comparisons with mammalian bone, we suggest thorough, phylogenetic examinations of regulatory pathways, studies of structure and mechanical properties and surveys of the presence/absence of bone cells in fishes. Insights gained into the micro-/nanolevel structure and architecture of fish bone, its mechanical properties and its physiology in health and disease will contribute to the discipline of fish skeletal biology, but may also help answer questions of basic bone biology.

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Section: Modeling: Evidence For and Implications In Acellular Bonementioning

confidence: 99%

The enigmas of bone without osteocytes

Shahar¹,

Dean²

2013

BoneKEy Reports

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“…Deschamps et al. () also found that sustained exercise seems to be a suitable approach to prevent aggravation of vertebrae anomalies in juvenile trouts. Indeed, in resting trouts, sub‐optimal mechanical stimuli could alter and/or delay vertebrae mineralization during growth, prevent normal remodeling processes and also lead to inappropriate bone condition, unable to resist strong and sudden mechanical pressure.…”

Section: In Teleost Fish Genetic Factors Inappropriate Nutrition Anmentioning

confidence: 96%

“…In salmonids, mineral recirculation can result from various demineralization processes: osteoclasis (bone resorption by osteoclasts), periosteocytal osteolysis (local resorption of bone surface by osteocytes), or halastasy (diffuse demineralization without organic matrix destruction) (Kacem et al., ; Kacem and Meunier, ; Deschamps, ). Bone remodelling is a permanent phenomenon and seems to be a compromise between the necessity to mobilize vertebral mineral ions in response to various physiological demands, and the necessity to maintain vertebral strength against mechanical constraints, in optimizing the allocation of calcium and phosphorus (see the work of Deschamps et al., , ,b). In severe cases, anomalies of vertebrae centra and/or arches are associated with macroscopic deviations of the vertebral axis, i.e.…”

Section: In Teleost Fish Genetic Factors Inappropriate Nutrition Anmentioning

confidence: 99%

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Architecture, mineralization and development of the axial skeleton in Acipenseriformes, and occurrences of axial anomalies in rearing conditions; can current knowledge in teleost fish help?

Leprévost

Sire

2014

J. Appl. Ichthyol.

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International audienceWe review current knowledge of axial skeleton biology in Acipenseriformes with the aim to know whether available data can help in understanding axial anomalies (anomalies of the vertebral column) in reared sturgeons or if further investigations are needed prior to undertake such analysis. In particular, accurate data on axial skeleton development, structure and mineralization are required to understand these pathologies. We show that such knowledge is fragmented and incomplete when compared to the information available in teleost fish. In Acipenseriformes, we only know that (i) the axial skeleton morphology is highly distinctive, as mostly cartilaginous, (ii) the vertebrae are composed of several elements organized around a persistent and unconstricted notochord, and (iii) mineralization only concerns a few of these elements and occurs late in ontogeny, but virtually no descriptions demonstrating the presence of bone (perichondral, membranous...) or mineralized cartilage is available in the literature. In addition, few studies concern axial anomalies in the wild or in rearing conditions, and the determinism of these pathologies is largely unknown. This is in contrast with the numerous studies dealing with the axial skeleton and its anomalies in many farmed teleost species, in which axial anomalies can result from numerous factors, such as unfavourable abiotic conditions, inappropriate nutrition and genetic factors. However, even if some parallels can be established between teleosts and sturgeons, it appears that current knowledge of the axial skeleton in teleosts may not help much in the study of axial anomalies in sturgeons. Knowledge of axial skeleton biology in sturgeon has to be therefore deeply improved prior to undertake investigations focusing on these pathologies

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“…Various skeletal anomalies, including axial skeleton deformities, occur in many reared teleost species and their onset is known to be the result of numerous factors: for example, unfavorable environmental conditions, inappropriate nutrition, genetics (Boglione et al, ). In salmonids, for instance, several studies demonstrated the link between bone mineralization and vertebral health (Deschamps, Girondot, Labbé, & Sire, ; Deschamps, Labbé, et al, ; Deschamps et al, ; Kacem & Meunier, ). In sturgeons, however, the development, mineralization and architecture of the vertebral column are poorly documented as revealed in a recent review of the literature (Leprévost & Sire, ).…”

Section: Introductionmentioning

confidence: 99%

Identification of a new mineralized tissue in the notochord of reared Siberian sturgeon (Acipenser baerii)

Leprévost

Azaı̈s

Trichet

et al. 2017

Journal of Morphology

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In a study aiming to improve knowledge on the mineralization of the axial skeleton in reared Siberian sturgeon (Acipenser baerii Brandt, 1869), we discovered a new mineralized tissue within the notochord. To our knowledge, such a structure has never been reported in any vertebrate species with the exception of the pathological mineralization of the notochord remains in degenerative intervertebral disks of mammals. Here, we describe this enigmatic tissue using X-ray microtomography, histological analyses and solid state NMR-spectroscopy. We also performed a 1-year monitoring of the mineral content (MC) of the notochord in relation with seasonal variations of temperature. In all specimens studied from 2-year-old juveniles onwards, this mineralized structure was found within a particular region of the notochord called funiculus. This feature first appears in the abdominal region then extends posteriorly with ageing, while the notochord MC also increases. The mineral phase is mainly composed of amorphous calcium phosphate, a small amount of which changes into hydroxyapatite with ageing. The putative role of this structure is discussed as either a store of minerals available for the phosphocalcic metabolism, or a mechanical support in a species with a poorly mineralized axial skeleton. A pathological feature putatively related to rearing conditions is also discussed.

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Sustained exercise improves vertebral histomorphometry and modulates hormonal levels in rainbow trout

Cited by 35 publications

References 69 publications

The enigmas of bone without osteocytes

The enigmas of bone without osteocytes

Architecture, mineralization and development of the axial skeleton in Acipenseriformes, and occurrences of axial anomalies in rearing conditions; can current knowledge in teleost fish help?

Identification of a new mineralized tissue in the notochord of reared Siberian sturgeon (Acipenser baerii)

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