Sustained Efficacy of Nevirapine in Combination with Two Nucleoside Analogues in the Treatment of HIV-Infected Patients: A 48-Week Retrospective Multicenter Study

Allan, P S; Arumainayagam, Joseph; Harindra, V; Tobin, Jenny; Browning, Meghen B.; Yoganathan, Kathir; Wade, A; S, Das

doi:10.1310/4nb4-1gx6-4xvk-pbgl

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…[50][51][52][53] Comparatively, adult first-line ART regimens report viral suppression rates between 79% in observational studies 54 and 85-98% in clinical trials. 52,[55][56][57][58] By combining recent studies of potent ART regimens in adolescents and young adults, we estimate that only 51% achieve viral suppression to less than 400 copies/ml as indicated in Table 1.…”

Section: Viral Suppressionmentioning

confidence: 99%

The Adolescent and Young Adult HIV Cascade of Care in the United States: Exaggerated Health Disparities

Zanoni

Mayer²

2014

AIDS Patient Care and STDs

354

315

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Little is known about how adolescents and young adults contribute to the declines in the cascade of care from HIV-1 diagnosis to viral suppression. We reviewed published literature from the Unites States reporting primary data for youth (13-29 years of age) at each stage of the HIV cascade of care. Approximately 41% of HIVinfected youth in the United States are aware of their diagnosis, while only 62% of those diagnosed engage medical care within 12 months of diagnosis. Of the youth who initiate antiretroviral therapy, only 54% achieve viral suppression and a further 57% are not retained in care. We estimate less than 6% of HIV-infected youth in the United States remain virally suppressed. We explore the cascade of care from HIV diagnosis through viral suppression for HIV-infected adolescents and young adults in the United States to highlight areas for improvement in the poor engagement of the infected youth population.

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