Sustained Achromobacter Xylosoxidans Bacteremia in a Patient with Adenocarcinoma of the Colon

Enríquez, M A Velázquez; Favini, Andi; Curl, Kevin

doi:10.29046/tmf.015.1.003

Cited by 1 publication

(3 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One of the main features of our population was their low immunocompromised rate. Compared to the literature [3, 14, 18, 20] more than 50% of our patients did not meet the immunosuppression criteria [23]. Achromobacter spp.…”

Section: Discussionmentioning

confidence: 57%

“…Such mechanical ventilation association confirmed the nosocomial character of pneumonia in our study and revived the question about Achromobacter spp. digestive carriage, which remains controversial [7, 11, 14, 34]. Although the gastro-pulmonary route is not considered to be the major route for the development of VAP, gastric colonization remains a potential endogenous source of infection [32].…”

Section: Discussionmentioning

confidence: 99%

“…Infections related to these bacteria are considered mainly associated to an immunocompromised status [3, 14, 18, 20]. However, numerous cases of Achromobacter infection occurring in immunocompetent patients have been published [11, 12, 15, 16].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Achromobacter spp. healthcare associated infections in the French West Indies: a longitudinal study from 2006 to 2016

et al. 2019

View full text Add to dashboard Cite

Background Bacteria of the Achromobacter genus, more particularly xylosoxidans species, are responsible for various healthcare associated infections (HAI) which are increasingly described since the last decade. Cystic fibrosis (CF) patients are considered as potential reservoirs in hospitals. We performed a retrospective study to estimate the frequencies of Achromobacter spp. HAI among patients from French West Indies, to determine characteristics of infected patients and establish a possible link between CF and infections. Methods All adults with at least one Achromobacter spp. positive sample and infection criteria in accordance with European official definitions of HAI, hospitalized in University Hospital of Martinique from 2006 to 2016 for more than 48 h, were included. Patient clinical features, immune status and underlying diseases were obtained from medical files. A list of CF patients was given by clinicians. Antibiotic-susceptibility profiles of the strains were determined using an automated method. Results Mean incidence density was 0.038/1000 days of hospitalization. Achromobacter spp. HAI evolved as an endemic situation with a low but pretty much stable incidence rate over the 11-year observation period. An epidemic peak was noticed in 2013. Among the 66 included patients, 56.1% were immunocompetent and no one had CF. Pneumonia and bacteraemia were the two main HAI. Among the 79 isolated strains, 92.4% were resistant to at least 1 major antibiotic and 16.4% met the definition of multidrug-resistant bacteria. Conclusions This microorganism, little known in our country because of the scarcity of CF patients, represents a threat for both immunosuppressed and immunocompetent patients and a therapeutic challenge because of its high resistance.

show abstract