Sustainable Synthetic Approaches Involving Thiocyanation and Sulfur- Cyanation: An Update

Abstract

This review highlights the achievements in the synthesis of organic thiocyanates (OTCs) over the past five years (late 2015 to mid-2019) and is intended as a follow-up on our tutorial review published in Chemical Society Reviews in 2016. The discussion places a special emphasis on sustainable synthetic approaches involving thiocyanation or sulfur-cyanation. The large number of contributions within this short period of time clearly indicates that the chemistry of OTCs provides a growing interest and a rapid evolution.

Recent progress of direct thiocyanation reactions

“…Thiocyanates are a class of organic compounds containing SCN groups, which are commonly found in a variety of natural products, synthetic drugs, and bioactive molecules. 1 These compounds display a variety of biological activities, such as antifungal, antibacterial, anti-parasite, anticancer, and so on. Thus, they have important applications in medicine and other fields (Fig.…”