Sustainable synthesis of single crystalline sulphur-doped graphene quantum dots for bioimaging and beyond

Sangam, Sujata; Gupta, Apoorv; Shakeel, Adeeba; Bhattacharya, Rohan; Sharma, Arun Kumar; Suhag, Deepa; Chakrabarti, Sandip; Garg, S.K.; Chattopadhyay, S.; Basu, Biswarup; Kumar, Vinod; Rajput, Satyendra K.; Dutta, Malay Kishore; Mukherjee, Monalisa

doi:10.1039/c8gc01638k

Cited by 114 publications

(93 citation statements)

References 75 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Of course, in addition to the N‐doped, there is also S‐doped in heteroatom doping. For example, S‐doped BCDs were prepared using molasses as a carbon source by heating for 4 h in a 180 °C autoclave. The particle size of the S‐doped BCDs prepared was about 3.5 nm, and the quantum yield reached 47%.…”

Section: Methods For the Synthesis Of Bcdsmentioning

confidence: 99%

See 1 more Smart Citation

Biomass‐Derived Carbon Dots and Their Applications

Meng

Bai

Wang

et al. 2019

Energy & Environ Materials

324

172

View full text Add to dashboard Cite

Carbon dots (CDs) have received much attention due to their superior properties including water solubility, low toxicity, biocompatibility, small size, fluorescence, and ease of modification. The use of a more environmentally friendly method to prepare high‐quality CDs is still an urgent question waiting for solve. The use of renewable, inexpensive, and green biomass resources not only meets the urgent need for large‐scale synthesis biomass CDs (BCDs), but also promotes the development of sustainable applications. In this article, we summarize the representative methods for synthesizing BCDs in green and simple ways using biomass as a carbon source, including hydrothermal carbonization, and microwave, pyrolysis. The prepared BCDs have a uniform particle size distribution and a relatively high throughput, which provide a method to scale up industrial production. Moreover, the integration of specific optical properties, that is, tunable photoluminescence and up‐photoluminescence, has led to remarkable use in bioimaging, sensing, and drug delivery. But the current review is not particularly comprehensive for BCDs. Therefore, we now provide a review focusing on the synthesis, properties, and recent advances in BCDs in biosensing, bioimaging, optoelectronics, and catalytic applications.

show abstract

Section: Methods For the Synthesis Of Bcdsmentioning

confidence: 99%

“…The BCDs show a high degree of solubility in water, and these BCDs are outstanding probes for in vitro bioimaging. Besides, Sangam et al . prepared BCDs via hydrothermal route from bio‐waste.…”

Section: Applications Of Bcdsmentioning

confidence: 99%

Biomass‐Derived Carbon Dots and Their Applications

Meng

Bai

Wang

et al. 2019

Energy & Environ Materials

324

172

View full text Add to dashboard Cite

show abstract

“…Similar with graphene, GQDs have capability to bind with a variety of aromatic bimolecular through the π-π stacking interaction and/or electrostatic binding. However compared with graphene sheets, GQDs exhibit improved biocompatibility and minimal toxicity [16][17][18], making them more promising materials for delivering of biologically active cargoes into living systems. In recent years, many researchers have been dedicated to the application of GQDs in drug delivery systems [19][20][21].…”

Section: Introductionmentioning

confidence: 99%

Synthesis of graphene quantum dots and their applications in drug delivery

et al. 2020

View full text Add to dashboard Cite

This review focuses on the recent advances in the synthesis of graphene quantum dots (GQDs) and their applications in drug delivery. To give a brief understanding about the preparation of GQDs, recent advances in methods of GQDs synthesis are first presented. Afterwards, various drug delivery-release modes of GQDs-based drug delivery systems such as EPR-pH delivery-release mode, ligand-pH delivery-release mode, EPR-Photothermal delivery-Release mode, and Core/Shell-photothermal/magnetic thermal delivery-release mode are reviewed. Finally, the current challenges and the prospective application of GQDs in drug delivery are discussed.

show abstract

“…Moreover, the ratio of D and G band intensity (I D /I G ) is 0.89, which represents the crystalline and graphitic nature of B,N-GQDs [33]. The XRD patterns of B,N-GQDs also show a broad peak at 2θ of 26.0 • and a small peak at 2θ of 40.3 • , which are the characteristic peak of (002) interlayer spacing and (100) in-plane lattice spacing of graphene in B,N-GQDs structure ( Figure S1c, Supplementary materials) [34].…”

Section: Characterization Of Bn-gqdsmentioning

confidence: 90%

Ultrasensitive Detection of Tetracycline Using Boron and Nitrogen Co-Doped Graphene Quantum Dots from Natural Carbon Source as the Paper-Based Nanosensing Probe in Difference Matrices

2020

View full text Add to dashboard Cite

Herein, the boron and nitrogen co-doped 0-dimensional graphene quantum dots (B,N-GQDs) with high quantum yield (QY) were synthesized via microwave-assisted hydrothermal method at 170 °C for 20 min using fresh passion fruit juice and boric acid as the starting materials. The 3–6 layers of B,N-GQDs with mean particle size of 9 ± 1 nm were then used for ultra-sensitive and selective detection of tetracycline in aqueous and biological media. The hybridization of boron and nitrogen atoms into the GQD structures increases the intensity of electronegative, resulting in the enhancement of QY to 50 ± 1%. The B,N-GQDs show their excellent analytical performance on tetracycline determination after 2 min of reaction under an optimal condition at pH 5. The linear range of 0.04–70 µM and with limits of detection (LOD) of 1 nM in phosphate buffer saline (PBS), 1.9 nM in urine and 2.2 nM in human serum are obtained. Moreover, the high selectivity of tetracycline by B,N-GQDs over the other 23 interferences is observed. The π-π interaction and electron donor-acceptor principle play pivotal roles in enhancing the ultra-sensitivity and selectivity of B,N-GQDs toward TC detection. Moreover, the B, N-GQD based paper nanosensor exhibits an excellent analytical performance on visual detection of 0.1–30 µM TC in human serum. Results of this study clearly indicate the feasibility of synthesis of B,N-GQDs derived from passion fruit juice for ultrasensitive tetracycline detection, which can open an avenue to use natural products for the preparation of environmentally benign and biocompatible carbon nanomaterials for highly sensitive detection of drugs, antibiotics, organic compounds and biomarkers.

show abstract

Sustainable synthesis of single crystalline sulphur-doped graphene quantum dots for bioimaging and beyond

Abstract: Waste-driven single crystalline sulphur-doped GQDs are synthesized via a green hydrothermal route with the highest quantum yield and excellent biocompatibility for bioimaging.

Cited by 114 publications

References 75 publications

Biomass‐Derived Carbon Dots and Their Applications

Biomass‐Derived Carbon Dots and Their Applications

Synthesis of graphene quantum dots and their applications in drug delivery

Ultrasensitive Detection of Tetracycline Using Boron and Nitrogen Co-Doped Graphene Quantum Dots from Natural Carbon Source as the Paper-Based Nanosensing Probe in Difference Matrices

Contact Info

Product

Resources

About