Sustainable–Green Synthesis of Silver Nanoparticles Using Aqueous Hyssopus officinalis and Calendula officinalis Extracts and Their Antioxidant and Antibacterial Activities

Balčiūnaitienė, Aistė; Puzerytė, Viktorija; Radenkovs, Vitālijs; Krasnova, I.; Memvanga, Patrick B.; Viškelis, Pranas; Štreimikytė, Paulina; Viškelis, Pranas

doi:10.3390/molecules27227700

Cited by 10 publications

(10 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Figure 9 indicates the AA inhibition potency of Ag 2 ONPs. Our results of green Ag 2 ONPs substantiate through the S. thea, R. virgata, Calendula officinalis, and mediated Ag 2 ONPs [52,58,60].…”

Section: Alpha-amylase Inhibition (Aa) Assaysupporting

confidence: 72%

Biogenic Synthesis of Multifunctional Silver Oxide Nanoparticles (Ag2ONPs) Using Parieteria alsinaefolia Delile Aqueous Extract and Assessment of Their Diverse Biological Applications

et al. 2023

View full text Add to dashboard Cite

Green nanotechnology has made the synthesis of nanoparticles a possible approach. Nanotechnology has a significant impact on several scientific domains and has diverse applications in different commercial areas. The current study aimed to develop a novel and green approach for the biosynthesis of silver oxide nanoparticles (Ag2ONPs) utilizing Parieteria alsinaefolia leaves extract as a reducing, stabilizing and capping agent. The change in color of the reaction mixture from light brown to reddish black determines the synthesis of Ag2ONPs. Further, different techniques were used to confirm the synthesis of Ag2ONPs, including UV-Visible spectroscopy, Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscope (SEM), Energy-dispersive X-ray spectroscopy (EDX), zeta potential and dynamic light scattering (DLS) analyses. The Scherrer equation determined a mean crystallite size of ~22.23 nm for Ag2ONPs. Additionally, different in vitro biological activities have been investigated and determined significant therapeutic potentials. Radical scavenging DPPH assay (79.4%), reducing power assay (62.68 ± 1.77%) and total antioxidant capacity (87.5 ± 4.8%) were evaluated to assess the antioxidative potential of Ag2ONPs. The disc diffusion method was adopted to evaluate the antibacterial and antifungal potentials of Ag2ONPs using different concentrations (125–1000 μg/mL). Moreover, the brine shrimp cytotoxicity assay was investigated and the LC50 value was calculated as 2.21 μg/mL. The biocompatibility assay using red blood cells (<200 μg/mL) confirmed the biosafe and biocompatible nature of Ag2ONPs. Alpha-amylase inhibition assay was performed and reported 66% inhibition. In conclusion, currently synthesized Ag2ONPs have exhibited strong biological potential and proved as an attractive eco-friendly candidate. In the future, this preliminary research work will be a helpful source and will open new avenues in diverse fields, including the pharmaceutical, biomedical and pharmacological sectors.

show abstract

Section: Alpha-amylase Inhibition (Aa) Assaysupporting

confidence: 72%

Biogenic Synthesis of Multifunctional Silver Oxide Nanoparticles (Ag2ONPs) Using Parieteria alsinaefolia Delile Aqueous Extract and Assessment of Their Diverse Biological Applications

et al. 2023

View full text Add to dashboard Cite

show abstract

“…There is no report on the use of C. officinalis plant extract in the green synthesis of ZnO NPs. However, its use in the synthesis of silver and selenium NPs has been reported 43,44 …”

Section: Resultsmentioning

confidence: 99%

Green and eco‐friendly biosynthesis of zinc oxide nanoparticles using Calendula officinalis flower extract: Wound healing potential and antioxidant activity

Aydin Acar,

Gencer,

Pehlivanoglu

et al. 2023

International Wound Journal

View full text Add to dashboard Cite

This study aimed to produce zinc oxide nanoparticles with Calendula officinalis flower extract (Co‐ZnO NPs) using the green synthesis method. In addition, the antioxidant and wound healing potential of synthesized ZnO NPs were evaluated. The absorbance band at 355 nm, which is typical for ZnO NPs, was determined from the UV–Vis absorbance spectrum. The energy‐dispersive X‐ray spectroscopy (EDS) measurements revealed a high zinc content of 42.90%. The x‐ray diffractometer data showed Co‐ZnO NPs with an average crystallite size of 17.66 nm. The Co‐ZnO NPs did not have apparent cytotoxicity up to 10 μg/mL (IC50 25.96 μg/mL). C. officinalis ZnO NPs showed partial cell migration and percent wound closure (69.1%) compared with control (64.8%). In addition, antioxidant activities of Co‐ZnO NPs with 2,2'‐azino‐bis(3‐ethylbenzothiazoline‐6‐sulfonic acid) (ABTS) and 2,2 diphenyl‐1 picrylhydrazil (DPPH) were evaluated and radical scavenging activity of 33.49% and 46.63%, respectively, was determined. These results suggest that C. officinalis extract is an effective reducing agent for the green synthesis of ZnO NPs with significant antioxidant and wound healing potential.

show abstract

“…The surface modification of metallic materials with peppermint essential oils was demonstrated to have bacteriostatic effects on Gram-positive bacteria and prevent biofilm formation [ 20 ]. Calendula officinalis (CO) is a medicinal herb also known as pot marigold [ 21 , 22 ]. CO flower extract consists of carotenes, flavonoids, terpenoids, triterpenoids, polyphenols, phenolic acids, quinines, coumarins, and other constituents [ 23 , 24 ].…”

Section: Introductionmentioning

confidence: 99%

“…In comparison to cinnamon and clove essential oils, CO flower extracts have additional biological effects, including the enhancement of cell proliferation/migration and the promotion of collagen metabolism and angiogenesis at the wound site [ 27 , 28 ]. Furthermore, CO flower extracts have been applied for the treatment of skin burns, ulcerations, inflammation, and wounds [ 22 , 26 ]. The pharmacological activity of CO extract can be enhanced via incorporation into a polymeric matrix with controlled release over time for wound healing [ 21 , 27 ].…”

Section: Introductionmentioning

confidence: 99%

Physicochemical Characterization, Biocompatibility, and Antibacterial Properties of CMC/PVA/Calendula officinalis Films for Biomedical Applications

Hung

Chiang

Lee³

et al. 2023

Polymers

View full text Add to dashboard Cite

This study reports a carboxymethyl cellulose (CMC)/polyvinyl alcohol (PVA) composite film that incorporates Calendula officinalis (CO) extract for biomedical applications. The morphological, physical, mechanical, hydrophilic, biological, and antibacterial properties of CMC/PVA composite films with various CO concentrations (0.1%, 1%, 2.5%, 4%, and 5%) are fully investigated using different experiments. The surface morphology and structure of the composite films are significantly affected by higher CO concentrations. X-ray diffraction (XRD) and Fourier transform infrared spectrometry (FTIR) analyses confirm the structural interactions among CMC, PVA, and CO. After CO is incorporated, the tensile strength and elongation upon the breaking of the films decrease significantly. The addition of CO significantly reduces the ultimate tensile strength of the composite films from 42.8 to 13.2 MPa. Furthermore, by increasing the concentration of CO to 0.75%, the contact angle is decreased from 15.8° to 10.9°. The MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] assay reveals that the CMC/PVA/CO-2.5% and CMC/PVA/CO-4% composite films are non-cytotoxic to human skin fibroblast cells, which is favorable for cell proliferation. Remarkably, 2.5% and 4% CO incorporation significantly improve the inhibition ability of the CMC/PVA composite films against Staphylococcus aureus and Escherichia coli. In summary, CMC/PVA composite films containing 2.5% CO exhibit the functional properties for wound healing and biomedical engineering applications.

show abstract

Sustainable–Green Synthesis of Silver Nanoparticles Using Aqueous Hyssopus officinalis and Calendula officinalis Extracts and Their Antioxidant and Antibacterial Activities

Cited by 10 publications

References 55 publications

Biogenic Synthesis of Multifunctional Silver Oxide Nanoparticles (Ag2ONPs) Using Parieteria alsinaefolia Delile Aqueous Extract and Assessment of Their Diverse Biological Applications

Biogenic Synthesis of Multifunctional Silver Oxide Nanoparticles (Ag2ONPs) Using Parieteria alsinaefolia Delile Aqueous Extract and Assessment of Their Diverse Biological Applications

Green and eco‐friendly biosynthesis of zinc oxide nanoparticles using Calendula officinalis flower extract: Wound healing potential and antioxidant activity

Physicochemical Characterization, Biocompatibility, and Antibacterial Properties of CMC/PVA/Calendula officinalis Films for Biomedical Applications

Contact Info

Product

Resources

About