Sustainable development of Draksha- Beeja extract loaded gelatin and starch-based green and biodegradable mats for potential tissue engineering applications

Das, Pratik; Chakravarty, T.; Roy, Arka Jyoti; Manna, Suvendu; Nandi, Samit Kumar; Basak, Piyali

doi:10.1016/j.scp.2023.101134

Cited by 2 publications

(3 citation statements)

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“…This polymer is highly biocompatible [ 33 , 38 ], eco-friendly [ 67 ], and bio-stable. It is a promising candidate for hydrogel applications due to its water absorption capacity, as well as its abundance, and plain structure [ 4 ].…”

Section: Polymersmentioning

confidence: 99%

“…Gelatin is a natural polymer resulting from the hydrolysis and controlled denaturation of collagen at high temperatures [ 6 , 11 , 61 , 83 ]. It is ubiquitous [ 84 ], eco-friendly [ 67 , 85 , 86 ], sustainable [ 85 ], and recyclable [ 84 ].…”

Section: Polymersmentioning

confidence: 99%

“…It is low-cost [ 98 , 130 , 132 , 134 , 176 , 177 ] and possesses good swelling properties [ 78 , 178 ], providing a moist environment and promoting effective hydration of the wound area [ 179 , 180 ]. Furthermore, it is renewable [ 130 , 131 ] and eco-friendly [ 67 , 131 , 132 , 133 , 134 , 154 , 178 ].…”

Section: Polymersmentioning

confidence: 99%

See 2 more Smart Citations

Hydrogels in Cutaneous Wound Healing: Insights into Characterization, Properties, Formulation and Therapeutic Potential

Ribeiro,

Simões,

Vitorino

et al. 2024

Gels

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Hydrogels are polymeric materials that possess a set of characteristics meeting various requirements of an ideal wound dressing, making them promising for wound care. These features include, among others, the ability to absorb and retain large amounts of water and the capacity to closely mimic native structures, such as the extracellular matrix, facilitating various cellular processes like proliferation and differentiation. The polymers used in hydrogel formulations exhibit a broad spectrum of properties, allowing them to be classified into two main categories: natural polymers like collagen and chitosan, and synthetic polymers such as polyurethane and polyethylene glycol. This review offers a comprehensive overview and critical analysis of the key polymers that can constitute hydrogels, beginning with a brief contextualization of the polymers. It delves into their function, origin, and chemical structure, highlighting key sources of extraction and obtaining. Additionally, this review encompasses the main intrinsic properties of these polymers and their roles in the wound healing process, accompanied, whenever available, by explanations of the underlying mechanisms of action. It also addresses limitations and describes some studies on the effectiveness of isolated polymers in promoting skin regeneration and wound healing. Subsequently, we briefly discuss some application strategies of hydrogels derived from their intrinsic potential to promote the wound healing process. This can be achieved due to their role in the stimulation of angiogenesis, for example, or through the incorporation of substances like growth factors or drugs, such as antimicrobials, imparting new properties to the hydrogels. In addition to substance incorporation, the potential of hydrogels is also related to their ability to serve as a three-dimensional matrix for cell culture, whether it involves loading cells into the hydrogel or recruiting cells to the wound site, where they proliferate on the scaffold to form new tissue. The latter strategy presupposes the incorporation of biosensors into the hydrogel for real-time monitoring of wound conditions, such as temperature and pH. Future prospects are then ultimately addressed. As far as we are aware, this manuscript represents the first comprehensive approach that brings together and critically analyzes fundamental aspects of both natural and synthetic polymers constituting hydrogels in the context of cutaneous wound healing. It will serve as a foundational point for future studies, aiming to contribute to the development of an effective and environmentally friendly dressing for wounds.

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Section: Polymersmentioning

confidence: 99%

Section: Polymersmentioning

confidence: 99%

See 1 more Smart Citation

Hydrogels in Cutaneous Wound Healing: Insights into Characterization, Properties, Formulation and Therapeutic Potential

Ribeiro,

Simões,

Vitorino

et al. 2024

Gels

View full text Add to dashboard Cite

show abstract

A benign synergism of O ₂ plasma and protein biopolymer for improving some properties of polyester fabrics

Mowafi,

El-Sayed

2024

The Journal of The Textile Institute

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Sustainable development of Draksha- Beeja extract loaded gelatin and starch-based green and biodegradable mats for potential tissue engineering applications

Cited by 2 publications

References 73 publications

Hydrogels in Cutaneous Wound Healing: Insights into Characterization, Properties, Formulation and Therapeutic Potential

Hydrogels in Cutaneous Wound Healing: Insights into Characterization, Properties, Formulation and Therapeutic Potential

A benign synergism of O ₂ plasma and protein biopolymer for improving some properties of polyester fabrics

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Sustainable development of Draksha- Beeja extract loaded gelatin and starch-based green and biodegradable mats for potential tissue engineering applications

Cited by 2 publications

References 73 publications

Hydrogels in Cutaneous Wound Healing: Insights into Characterization, Properties, Formulation and Therapeutic Potential

Hydrogels in Cutaneous Wound Healing: Insights into Characterization, Properties, Formulation and Therapeutic Potential

A benign synergism of O 2 plasma and protein biopolymer for improving some properties of polyester fabrics

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A benign synergism of O ₂ plasma and protein biopolymer for improving some properties of polyester fabrics