Sustainable and Well-Dispersed Cu-Doped Magnetic Vortex Nanorings for Highly Specific Separation of His-Rich Proteins
Xingyan Wang,
Yingying Niu,
Kaili Wang
et al.
Abstract:The combination of magnetic nanomaterials with the immobilized metal affinity (IMA) technique has emerged as a powerful method to specifically separate histidine (His)-rich proteins. However, obtaining a high-performance and sustainable magnetic adsorbent with good dispersibility and minimal copper leakage remains a major challenge. Herein, we propose a simple ligand-free method to acquire Cu-doped magnetic nanorings (Fe 3 O 4 −Cu NR) for the highly selective enrichment of His-rich proteins. Importantly, the F… Show more
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