Eco-Industrial Town (EIT) is one of the important policies of Thailand since 2011 aiming at developing operations of related parties in the target EITs. With emerging concepts, threats and challenges to Thailand, EIT framework and indicators need to be developed to be able to cope with them. This study aims to develop a framework and indicators for monitoring and evaluating progress of EIT implementation in the target EITs in Thailand. Methodology used in the study are the documentary research, two rounds of questionnaires distributed to 30 experts to gather feedback and recommendations and focus group discussion with 52 stakeholders from 6 target EITs in Thailand to gather feedback and recommendations. The results provided an EIT framework which contains of 6 perspectives, 32 dimensions, and 54 indicators which appropriate to EIT implementation in the Thailand context. Implication of the study is that the EIT framework, indicators and recommendations are useful for the future EITs in Thailand and EITs in other countries where under developing the project by selecting perspectives, dimensions, indicators, and recommendations that appropriate to their context.