Sustainability in Biobanking: Model of Biobank Graz

Sargsyan, Karine; Macheiner, Tanja; Story, Petra; Strahlhofer-Augsten, Manuela; Plattner, Katharina; Riegler, Skaiste; Granitz, G.; Bayer, Michaela; Huppertz, Berthold

doi:10.1089/bio.2015.0087

Cited by 24 publications

(11 citation statements)

References 10 publications

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“…17 For bio banks access to long-term public funding is crucial to be able to build up and maintain an infrastructure that allows establishing preanalytical quality control. 18,19 For clinical bio banks in particular, a long-term funding and cost recovery strategy is necessary for sustainable utilization. 19 In terms of sample logistics, one of the biggest challenges for a clinical biobank is the melding of research with clinical care.…”

Section: Resultsmentioning

confidence: 99%

Logistic Steps of Tissue Sample Processing in a Clinical Biobank - A Short Overview

Sargsyan¹

2017

ACP

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Human tissue samples, collected and stored based on standardized processes, enable high quality research in the field of biomedicine and life sciences. Most of the tissue biospecimens used in medical research are derived from patients and are collected, processed and stored by clinical biobanks. Clinical biobanks are usually situated in hospitals and operate directly at the interface between research and clinical care. This position requires specific steps adapted to the demands of both clinicians and researchers. This review aims to provide a short overview of the six most significant steps in sample handling and sample logistics in a clinical biobank. The described steps are crucial stages in the sample preservation process and have significant impact on quality of tissue biospecimens used in diagnostics and research. Biobank Graz, one of the largest clinical biobanks in Europe, collects, processes and stores tissue samples according to this workflow to provide high-quality samples and data for research and development.

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Section: Resultsmentioning

confidence: 99%

Logistic Steps of Tissue Sample Processing in a Clinical Biobank - A Short Overview

Sargsyan¹

2017

ACP

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“…18 One main reason is that fees charged by biobanks do not cover the real marginal costs for handling samples, let alone the average costs needed to maintain supply. A report commissioned by the Nottingham Health Science Biobank demonstrated that actual costs associated with biobanking were significantly higher than recognized by most researchers and funding bodies, with an average sample costing five to ten times more than estimated by the UK Medical Research Council.…”

Section: Discussionmentioning

confidence: 99%

Biobank sustainability: current status and future prospects

Doucet¹,

Yuille²,

Georghiou³

et al. 2017

BSAM

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Abstract:Biobanks play an important role in biomedical research that aims to understand cellular and molecular mechanisms underlying the development of diseases, and to improve interventions for human health. Despite financial support from mixed public funding streams, long-term sustainability of public biobanks remains a major concern. Review of the literature demonstrates that total cost-recovery strategies, as well as commercialization of research results or derived products, may not represent the best way to reach and maintain sustainability. Public biobanks require support by long-term investment and commitment from public and governmental sources, as well as support from industrial users. In this regard, this study suggests strategies to improve long-term sustainability, such as sample-sharing and biobank consolidation to reduce unit costs, embedding public biobanks in health care systems, and working to implement global funding mechanisms.

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“…Examination of how these dimensions make up the full picture of an institutions' or infrastructure's sustainability has been described in several publications. [5][6][7][8][9][10][11][12][13][14][15][16] It is very clear that modern, sustainable biobanking relies on quality samples that are fit for the purpose for their downstream use. Although early stage biobanks may focus on increasing their inventory, having well-documented, quality specimens that are able to support a research or clinical purpose is the key measure of success.…”

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confidence: 99%