Suspected withdrawal syndrome after cessation of St. Johnʼs wort

Dean, Angela J.; Moses, Geraldine; Vernon, J.

doi:10.1345/1542-6270(2003)37<150a:swsaco>2.0.co;2

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Safety Issues Relevant To Substance Use1

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2005

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“…Co-administration of hypericum and serotonergic agents such as antidepressants or methylenedioxymethamphetamine (MDMA, or Ecstasy) may also lead to serotonin toxicity [47]. Similarly to conventional antidepressants, hypericum may produce withdrawal symptoms after abrupt cessation of higher doses [48].…”

Section: Safety Issues Relevant To Substance Usementioning

confidence: 99%

Natural and complementary therapies for substance use disorders

Dean

2005

Current Opinion in Psychiatry

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Several pharmacological and psychosocial treatments for substance use disorders are solidly evidence-based and improve both individual and public health outcomes. At this stage, there remains insufficient evidence to support the use of natural and complementary therapies as a primary intervention for substance use disorders. Further clinical trials are required to clarify the potential role of particular agents.

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Section: Safety Issues Relevant To Substance Usementioning

confidence: 99%