Suspected allergy to local anaesthetics: follow‐up in 135 cases

Abstract

Reactions during local anaesthesia are rarely found to be an IgE-mediated LA allergy. Whenever the clinical picture is compatible with allergy, other allergens should also be tested.

Laryngoscopy in conscious patients with remifentanil: how useful is an “awake look”?

“…Application of topical anesthesia can be time-consuming and may neither provide adequate comfort nor blunt the gag reflex adequately in every patient. Patients also may present with a history of allergy to local anesthetics [8]. A simple, titratable, and rapid alternative to facilitate direct laryngoscopy in conscious patients would be useful.…”

The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics

“…Bhole et al pointed out the importance of other allergic elicitors such as chlorhexidine and latex [4]. In a Norwegian study about the work-up of 135 patients with suspected LA hypersensitivity reactions, only two patients were diagnosed as suffering from true LA allergy [5]. The first case was a delayed hypersensitivity reaction, and the second one was of the immediate type and was based on an open subcutaneous challenge test.…”

Excision biopsy in a patient with suspected local anaesthetic allergy: use of 0.9% saline with benzyl alcohol as local anaesthesia

“…Type I IgE‐mediated reactions are the most dangerous, and may result in anaphylaxis. Pruritus and urticaria may herald full‐blown anaphylaxis, and have been reported more frequently in test‐positive cases of LA allergy 3 . Delayed hypersensitivity‐type reactions presenting as contact dermatitis or oedema at the injection site are a more common presentation, and may occur as early as 2 h after injection 4 .…”

“…Harboe et al. 3 reviewed 135 cases of possible LA allergy referred to an allergy clinic. Of these, 2 cases (1.5%) had type 1 hypersensitivity to LA (1 to articaine–adrenaline and one to tetracaine–adrenaline), and 10 cases (7%) had IgE‐mediated allergy to other substances including chlorhexidine, latex, and triamcinolone.…”