Abstract. In this study, we propose a method to remove bio-signal distortions generated when the power is at transient condition in a high-powered portable medical device. To verify the method, three units were designed that consists of a main control unit, bio-signal measurement unit, and power unit. Also, each units were separated with galvanic isolation. For stable operation at the surge condition, the power unit was composed using push-pull converter topology. The design has been examined in both transient and steady state of the operating conditions. The experiment result shows that galvanic isolation between each units was efficient in high-powered potable medical device.