Susceptibilidade larval de populações de Aedes aegypti e Culex quinquefasciatus a inseticidas químicos

Campos, Jairo; Andrade, Carlos Fernando Salgueirosa de

doi:10.1590/s0034-89102003000400019

Cited by 27 publications

(16 citation statements)

References 7 publications

(8 reference statements)

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“…The RR values obtained in this work indicated temephos resistance in all of the populations evaluated. Temephos resistance was even found in Cuiabá in contrast to an earlier report from that locality (Campos & Andrade 2003), suggesting recent local resistance dissemination (MS/SVS 2007). High temephos RR values were found at localities from Northeast and Southeast Brazil, corroborating previous data , Macoris et al 2007, Montella et al 2007).…”

contrasting

confidence: 82%

The efficacy of a chitin synthesis inhibitor against field populations of organophosphate-resistant Aedes aegypti in Brazil

Fontoura

Bellinato

Valle

et al. 2012

Mem. Inst. Oswaldo Cruz

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Key words: Aedes aegypti -chitin synthesis inhibitors -temephos -deltamethrin -novaluron -cross-resistance Among the arboviruses transmitted by mosquitoes throughout the world, dengue is presently the most relevant; it is endemic to all of the continents, except Europe (Nogueira et al. 2001, Forattini 2002, Claro et al. 2004. Brazil has an alarming dengue incidence with several outbreaks all over the country and an increasing incidence of severe cases. Therefore, major public health campaigns target this disease (Teixeira et al. 1999, Câ-mara et al. 2007, MS/SVS 2009.Specific drugs and an effective vaccine against dengue virus are not yet available (Durbin & Whitehead 2010). Consequently, the only way to control the dengue epidemiological network is to target the virus' vector, Aedes aegypti (Medronho 2006. Although the elimination of potential Aedes breeding sites is increasingly considered a crucial component of dengue control, the utilisation of chemical insecticides is still a common measure. Until very recently, the most commonly used insecticides against Aedes in Brazil were the organophosphate temephos and the pyrethroid deltamethrin, which are used to control the larval and adult populations, respectively .The continuous use of chemical insecticides can lead to the dissemination of resistance and the consequent failure of the control efforts. Therefore, alternative methods of controlling disease-transmitting vectors are urgently needed. Two examples are entomopathogenic bacteria and insect growth regulators (IGRs). The biological insecticide Bacillus thuringiensis serovar israelensis (Bti) has been employed against Ae. aegypti in various municipalities of Brazil. However, the reduced field persistence of commercially available Bti formulations is an obstacle; under tropical conditions, the maximal residual effect observed lasted four weeks .In contrast to the classical chemical insecticides and biolarvicides, IGRs are not directly toxic, but act selectively on the development, metamorphosis or reproduction of the target insect species (Hoffmann & Lorenz 1998, Martins & Silva 2004. Among IGRs, the chitin synthesis inhibitors (CSIs) act by interfering with the synthesis or deposition of chitin on the exoskeleton or other chitinised internal structures, such as the peritrophic matrix (Merzendorf & Zimoch 2003, Merzendorf 2005.Novaluron is a CSI that is already utilised in agriculture. It is highly effective against Coleoptera, Homoptera and Lepidoptera larvae of several crop pests . It can act through ingestion, as verified in the larvae of the moth species Spodoptera littoralis and Helicoverpa armigera, or through contact, as reported with the flies Bemisia tabaci and Trialeurodes vaporariorum (Ishaaya et al. 1996(Ishaaya et al. , 1998. Novaluron is also efficient against Ae. aegypti larvae, as reported by Mulla et al. (2003) and Arredondo-jiménez and Valdez-Delgado (2006). Because novaluron is recommended by the World Health Organization for use in drinking water, it represents a potential tool in the con...

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contrasting

confidence: 82%

The efficacy of a chitin synthesis inhibitor against field populations of organophosphate-resistant Aedes aegypti in Brazil

Fontoura

Bellinato

Valle

et al. 2012

Mem. Inst. Oswaldo Cruz

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“…Embora no presente trabalho não tenha sido verificado o mecanismo metabólico envolvido na resistência aos inseticidas, modificações de esterases em populações brasileiras de C. quinquefasciatus para organofosforados já foram relatadas 4,9,21 . Entretanto, para os derivados da Avermectina, que geralmente são usados como antiparasitários em bovinos, equinos e ovinos e também como pesticidas agrícolas [22][23][24] , ainda não há registros na literatura de resistência no Brasil.…”

Section: Discussionunclassified

“…Suas larvas são capazes de se desenvolverem em diversos tipos de habitats, de esgotos à água limpa, com preferência para os primeiros [1][2][3] . Por estar relacionado à transmissão da filariose bancroftiana nas Américas, e em particular no Brasil, este inseto apresenta grande importância em saúde pública, gerando desafios administrativos e públicos para o seu controle 4 . Inseticidas organoclorados, organofosforados, carbamatos e piretróides têm sido largamente empregados para controlar mosquitos vetores de doenças em diversas partes do mundo.…”

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Suscetibilidade de larvas de Culex quinquefasciatus a diferentes inseticidas

Alves

Tibúrcio

Melo

2011

Rev. Soc. Bras. Med. Trop.

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RESUMOIntrodução: O presente estudo teve como objetivo avaliar a suscetibilidade de larvas de Culex quinquefasciatus a dois piretróides (Cipermetrina e Deltametrina), dois derivados da Avermectina (ivermectina e abamectina) e a um organofosforado (Temefós). Métodos: Larvas de 3 o e 4 o instares de C. quinquefasciatus foram expostas a diferentes concentrações destes (onze repetições) seguindo o protocolo da Organização Mundial de Saúde. Uma hora após a exposição, as larvas foram lavadas em água desclorada, transferidas para recipientes plásticos contendo água sem cloro, alimentadas e observadas por períodos de 24h, até se transformarem em adultos. Para a determinação das concentrações letais, os valores foram submetidos à análise de regressão usando o modelo probit pelo programa Minitab 15. Resultados: Diferenças entre as estimativas da CL 50 e CL 90 justificaram que a população de mosquitos testada apresenta heterogeneidade em resposta aos inseticidas, sendo a maior concentração utilizada para a CL 50 , a partir da análise de probit para o Temefós. Todos os inseticidas avaliados causaram mortalidade mais acentuada nas primeiras 24h exceto quando expostas à ivermectina. Conclusões: As larvas são suscetíveis a todos os inseticidas testados e há uma necessidade de um monitoramento dos inseticidas utilizados. Palavras-chaves:Culex. Inseticidas. Temefós. Piretróides. Avermectinas. ABSTRACT Introduction:This study aimed to assess the susceptibility of Culex quinquefasciatus larvae to two pyrethroids (Cypermethrin and Deltamethrin), two derivatives of Avermectin (Ivermectin and Abamectin) and an organophosphate (Temephos). Methods: Third-and fourth-instar larvae of C. quinquefasciatus were exposed to different concentrations of insecticides (eleven repetitions) according to the World Health Organization's protocol. One hour after exposure, larvae were washed in dechlorinated tap water, transferred to plastic containers containing water without chlorine, fed and observed for periods of 24h until reaching adulthood. To determine lethal concentrations, the obtained values were submitted to regression analysis using the probit model with the Minitab 15 program. Results: The highest concentration used for the LC 50 from probit analysis was for Temephos. The evaluated insecticides caused more pronounced larvae mortality in the first 24h with the exception of those exposed to ivermectin. Conclusions: This study demonstrates that larvae are susceptible to all tested insecticides and that there is a need for monitoring the use of insecticides.

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“…aegypti in the cosmotropical area has triggered several interventions by the public health authorities through synthetic insecticide application as the main means of control of the vector 30 . However, the mosquito resistance to organophosphates and carbamate insecticides 3,6,12,14 , along with the need of looking for methods of control that are less or nontoxic to man and to environment, has stimulated the search for new means of Ae. aegypti control.…”

Section: Introductionmentioning

confidence: 99%

[No Title Available]

Geris

Silva

et al. 2008

Rev. Inst. Med. trop. S. Paulo

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SUMMARYThe objective of this study was to evaluate the larvicidal activity of diterpenoids obtained from the oil-resin of Copaifera reticulata against Aedes aegypti larvae, the principal vector of dengue and urban yellow fever. Four diterpenes were obtained from oil-resin extraction with organic solvents and subsequent chromatographic and spectroscopic procedures allowed to isolation and identification of these compounds as 3-β-acetoxylabdan-8(17)-13-dien-15-oic acid (1), alepterolic acid (2), 3-β-hidroxylabdan-8(17)-en-15-oic acid (3), and ent-agatic acid (4). Each compound was previously dissolved in dimethylsulphoxide, and distilled water was added to obtain the desired concentrations. Twenty larvae of third instars were placed into plastic beckers, containing the solution test (25 mL), in a five repetitions scheme, and their mortality, indicated by torpor and darkening of the cephalic capsule, was recorded after 48h. Probit analyses were used to determine lethal concentrations (LC 50 and LC 90 ) and their respective 95% confidence intervals. This study showed that only diterpenoids 1 and 2 exhibited larvicidal properties with LC 50 of 0.8 ppm and 87.3 ppm, respectively, revealing the former as the most toxic compound against third instars of Ae. aegypti. Therefore, this compound seems to be an interesting source for new metabolite to be exploited.

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Susceptibilidade larval de populações de Aedes aegypti e Culex quinquefasciatus a inseticidas químicos

Cited by 27 publications

References 7 publications

The efficacy of a chitin synthesis inhibitor against field populations of organophosphate-resistant Aedes aegypti in Brazil

The efficacy of a chitin synthesis inhibitor against field populations of organophosphate-resistant Aedes aegypti in Brazil

Suscetibilidade de larvas de Culex quinquefasciatus a diferentes inseticidas

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