Surviving Childhood Cancer

Goldsby, Robert E.; Taggart, Denah; Ablin, Arthur R.

doi:10.2165/00148581-200608020-00001

Cited by 13 publications

(13 citation statements)

References 178 publications

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“…However, in 2012 we documented a standardized overall mortality rate of 5.3 without a significant difference between genders. We recognize that our mortality rate is higher compared with other Latin-American countries [27–29] in spite of the PMI program. Mexican children (<18 years) with cancer had an average lifespan of 10.8 years and therefore impede living on an average of 59.2 years [6], while in develop countries, the survival rate in childhood cancer is higher and better [30].…”

Section: Discussionmentioning

confidence: 74%

Descriptive Epidemiology in Mexican children with cancer under an open national public health insurance program

Rivera-Luna¹,

Shalkow-Klincovstein

Velasco-Hidalgo³

et al. 2014

BMC Cancer

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BackgroundAll the children registered at the National Council for the Prevention and Treatment of Childhood Cancer were analyzed. The rationale for this Federal Government Council is to financially support the treatment of all children registered into this system. All patients are within a network of 55 public certified hospitals nationwide.MethodsIn the current study, data from 2007 to 2012 are presented for all patients (0–18 years) with a pathological diagnosis of leukemia, lymphoma and solid tumors. The parameters analyzed were prevalence, incidence, mortality, and abandonment rate.ResultsA diagnosis of cancer was documented in 14,178 children. The incidence was of 156.9/million/year (2012). The median age was 4.9. The most common childhood cancer is leukemia, which occurs in 49.8% of patients (2007–2012); and has an incidence rate of 78.1/million/year (2012). The national mortality rate was 5.3/100,000 in 2012, however in the group between 15 to 18 years it reaches a level of 8.6.ConclusionsThe study demonstrates that there is a high incidence of childhood cancer in Mexico. In particular, the results reveal an elevated incidence and prevalence of leukemia especially from 0 to 4 years. Only 4.7% of these patients abandoned treatment. The clinical outcome for all of the children studied improved since the establishment of this national program.

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Section: Discussionmentioning

confidence: 74%

Descriptive Epidemiology in Mexican children with cancer under an open national public health insurance program

Rivera-Luna¹,

Shalkow-Klincovstein

Velasco-Hidalgo³

et al. 2014

BMC Cancer

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“…(Hudson et al, 2003;Aziz et al, 2006;Goldsby et al, 2006;Maule et al, 2007;Kurt et al, 2008;Mertens et al, 2008;Oeffinger et al, 2008) There is also some evidence that childhood cancer and its treatment can have persisting negative effects on parents (Hardy et al, 2008) in relation to both finance and lifestyle (Cohn et al, 2003).…”

mentioning

confidence: 99%

Trends in incidence of childhood cancer in Australia, 1983–2006

et al. 2010

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BACKGROUND: There are few population-based childhood cancer registries in the world containing stage and treatment data. METHODS: Data from the population-based Australian Paediatric Cancer Registry were used to calculate incidence rates during the most recent 10-year period (1997 -2006) and trends in incidence between 1983 and 2006 for the 12 major diagnostic groups of the International Classification of Childhood Cancer. RESULTS: In the period 1997 -2006, there were 6184 childhood cancer (at 0 -14 years) cases in Australia (157 cases per million children). The commonest cancers were leukaemia (34%), that of the central nervous system (23%) and lymphomas (10%), with incidence the highest at 0 -4 years (223 cases per million). Trend analyses showed that incidence among boys for all cancers combined increased by 1.6% per year from 1983 to 1994 but have remained stable since. Incidence rates for girls consistently increased by 0.9% per year. Since 1983, there have been significant increases among boys and girls for leukaemia, and hepatic and germ-cell tumours, whereas for boys, incidence of neuroblastomas and malignant epithelial tumours has recently decreased. For all cancers and for both sexes combined, there was a consistent increase ( þ 0.7% per year, 1983 -2006) at age 0 -4 years, a slight nonsignificant increase at 5 -9 years, and at 10 -14 years, an initial increase (2. 7% per year, 1983 -1996) followed by a slight nonsignificant decrease. CONCLUSION: Although there is some evidence of a recent plateau in cancer incidence rates in Australia for boys and older children, interpretation is difficult without a better understanding of what underlies the changes reported.

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“…Although the Australian childhood cancer incidence rate represents less than 1% of all invasive cancers diagnosed in this country, it is still the most common cause of disease-related death for children between 1–14 years of age in Australia (Australian Institute of Health and Welfare, 2009). Many survivors face significant long-term adverse health effects because of the cancer itself or as a result of treatment (Aziz et al , 2006; Goldsby et al , 2006; Kurt et al , 2008; Landier and Bhatia, 2008; Oeffinger et al , 2008). The diagnosis of cancer in a child also has a considerable and ongoing impact, both psychological and financial, on the families concerned (Cohn et al , 2003; Hardy et al , 2008).…”

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confidence: 99%

Population-based survival estimates for childhood cancer in Australia during the period 1997–2006

et al. 2010

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Background:This study provides the latest available relative survival data for Australian childhood cancer patients.Methods:Data from the population-based Australian Paediatric Cancer Registry were used to describe relative survival outcomes using the period method for 11 903 children diagnosed with cancer between 1983 and 2006 and prevalent at any time between 1997 and 2006.Results:The overall relative survival was 90.4% after 1 year, 79.5% after 5 years and 74.7% after 20 years. Where information onstage at diagnosis was available (lymphomas, neuroblastoma, renal tumours and rhabdomyosarcomas), survival was significantly poorer for more-advanced stage. Survival was lower among infants compared with other children for those diagnosed with leukaemia, tumours of the central nervous system and renal tumours but higher for neuroblastoma. Recent improvements in overall childhood cancer survival over time are mainly because of improvements among leukaemia patients.Conclusion:The high and improving survival prognosis for children diagnosed with cancer in Australia is consistent with various international estimates. However, a 5-year survival estimate of 79% still means that many children who are diagnosed with cancer will die within 5 years, whereas others have long-term health morbidities and complications associated with their treatments. It is hoped that continued developments in treatment protocols will result in further improvements in survival.

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Surviving Childhood Cancer

Cited by 13 publications

References 178 publications

Descriptive Epidemiology in Mexican children with cancer under an open national public health insurance program

Descriptive Epidemiology in Mexican children with cancer under an open national public health insurance program

Trends in incidence of childhood cancer in Australia, 1983–2006

Population-based survival estimates for childhood cancer in Australia during the period 1997–2006

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