Survival time of juvenile dogs with oral squamous cell carcinoma treated with surgery alone: A Veterinary Society of Surgical Oncology retrospective study

Abstract

To report the signalment, staging, surgical treatment, and survival time of juvenile dogs treated surgically for oral squamous cell carcinoma (OSCC).Study design: Retrospective study. Animals or sample population: Twenty-five dogs, <2 years of age with OSCC treated with surgery.Methods: Cases were solicited from the Veterinary Society of Surgical Oncology. Data retrieved included sex, breed, age, weight, clinical signs, tumor location, preoperative diagnostics and staging, histopathological diagnosis with margin evaluation, disease-free interval, and date and cause of death. A minimum follow-up time of 3 months was required for inclusion.Results: Eighteen dogs were <12 months of age, and seven were <24 months. Various breeds were represented, with a mean body weight of 22.3 ± 14.4 kg.No dogs had evidence of metastatic disease prior to surgery. All dogs underwent partial maxillectomy or mandibulectomy. Histological margins were complete in 24 dogs and incomplete in one. No dogs had evidence of metastatic

Recurrent Squamous Cell Carcinoma of the Submandibular Region after Surgery in a Dog: A Case Report

“…The recurrence of this tumor after surgery is in agreement with Lascelles et al (2000) who reported an average recurrence of 4-9 weeks (Lascelles et al, 2000). The survival time for SCC dogs after surgery alone with no evidence of metastasis has been reported to be an average of 92 to 4234 days (Sharma et al, 2021). In the current case, the dog died after about 33 days, so it is possible that the dog died from SCC metastasis.…”

“…As previously reported, SCC is commonly found in dogs with an average age of 8.8 years (Willcox et al, 2019). In addition, some previous reports found an average age of 10 years (Lascelles et al, 2000), but the condition can be found from 4 months to 14 years of age (Łojszczyk et al, 2021;Sharma et al, 2021). The effect of gender on cases of SCC is unclear.…”

“…There may be a large body surface area for contact with the tumor stimulants, such as ultraviolet light and chemical carcinogens. However, cases in small breeds, such as the poodle or Shih Tzu have also been reported (Sharma et al, 2021). The location of SCC has been found to vary.…”

Safety and Efficacy of an Oncolytic Adenovirus as an Immunotherapy for Canine Cancer Patients

“…Cutaneous and subcutaneous origins are the most frequent neoplasms, representing one-third of all diagnosed tumors in dogs [ 2 ]. Conventional therapies to treat canine tumors have certain disadvantages due to their low specificity, surgical limitations for non-accessible tumors [ 3 ], and the low availability of radiotherapy in some countries [ 4 , 5 , 6 , 7 ]. Due to these issues, immunotherapy is becoming one of the main pillars of anti-tumoral treatment research [ 8 ].…”

“…The most frequent tumors in dogs are cutaneous and subcutaneous, of epithelial origin, and the gold-standard therapies are either not available (radiotherapy) or are highly invasive procedures (surgery) [ 2 , 3 , 6 ]. The overall incidence of tumors determined to be of epithelial origin in dogs has been reported to be from 26 to 43%, in some cases being very aggressive and invasive tumors [ 1 , 2 ].…”