Survival time and its predictors among preterms in the neonatal period post-discharge in Busoga region-Uganda  June – July 2017

Opio, Charles; Malumba, Richard; Kagaayi, Joseph; Ajumobi, Olufemi; Kamya, Carol; Mukose, Aggrey; Yeka, Adoke; Muneza, Fiston; Kisaakye, Angela; Nalwadda, Christine; Waiswa, Peter

doi:10.37432/jieph.2019.2.2.19

Cited by 7 publications

(8 citation statements)

References 19 publications

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“…However, the finding is much higher than from a global report of high-income countries that includes Australia, Belgium and Canada 21. In addition, the findings were also higher than the studies conducted by Iran,13 Uganda,22 Tanzania23 and Nigeria 24. On the other hand, the finding of this study is lower than that of the studies conducted in Bahir Dar, Ethiopia16 and Ghana 25.…”

Section: Discussioncontrasting

confidence: 84%

“…The risk of preterm neonatal mortality is 2.7 times higher for preterm neonates who did not receive kangaroo mother’s care as compared with preterm neonates who did receive kangaroo mother’s care. This finding is supported by the studies conducted in Uganda and Ethiopia 20 22. Preterm with kangaroo mother care is advantageous to maintain cardiopulmonary and temperature stability.…”

Section: Discussionmentioning

confidence: 56%

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Escalating the limit of median survival time and predictors of mortality among preterm neonates in Northwest Ethiopia, 2021: a 1-year prospective follow-up study

et al. 2022

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ObjectivesTo examine the survival rate and predictors of mortality among preterm neonates in the neonatal intensive care unit at South Gondar public hospitals, 2021.DesignProspective follow-up study.SettingSouth Gondar public hospitals, Northwest, Ethiopia.ParticipantsWe recruited 283 preterm neonates who were admitted at neonatal intensive care unit at selected hospitals from 15 February 2020 to 22 January 2021.Outcome measuresThe primary outcome measure of this study was the survival rate of preterm neonates in the neonatal intensive care unit. Moreover, the study assessed the predictors for the occurrence of mortality by the Cox-proportional hazard model. Data were entered into Epi data V.4.2 and exported to Stata V.14 statistical software for analysis. The log-rank test determines the survival difference between predictor variables.ResultsA total of 283 preterm neonates, 61 died during the follow-up. Born from antepartum haemorrhage mother (adjusted HR (AHR)=2.2 (95% CI 1.10 to 4.37)), being small weight for gestational age (AHR=4.6 (95% CI 2.22 to 9.53)), not having kangaroo mother care practice initiated (AHR=2.7 (95% CI 1.39 to 7.74)), hypothermia (AHR=4.0 (95% CI 1.96 to 8.30)) and perinatal asphyxia (AHR=3.9 (95% CI 1.97 to 7.94)) were significant predictors of preterm neonate mortality.ConclusionIn this study, the preterm neonates survival rate (78.4%) and the median survival time (21 days) were found to be low. Preventing and managing the predictors, including an antepartum haemorrhagic mother, small weight for gestational age, hypothermia and prenatal asphyxia, is crucial. In addition, more emphasis should be placed on initiating universal kangaroo mother care practice soon after birth to increase the survival of preterm neonates.

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Section: Discussioncontrasting

confidence: 84%

Section: Discussionmentioning

confidence: 56%

Escalating the limit of median survival time and predictors of mortality among preterm neonates in Northwest Ethiopia, 2021: a 1-year prospective follow-up study

et al. 2022

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“…The studies were conducted from 2012 to 2020 among more than 11 Eastern Africa countries including 12 from Ethiopia represented by 14 studies [ 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 ]. Tanzania [ 14 , 45 , 46 , 47 ] and Uganda [ 12 , 48 , 49 , 50 ] represented by 04 studies, Besides, Burundi [ 51 , 52 ] and Eretria [ 53 , 54 ] represented by 02 studies. While Malawi [ 55 ], Kenya [ 56 ], Zambia [ 24 ], Sudan [ 25 ], Mozambique [ 57 ], and Zimbabwe [ 58 ] are represented by 01 studies.…”

Section: Resultsmentioning

confidence: 99%

“…While Malawi [ 55 ], Kenya [ 56 ], Zambia [ 24 ], Sudan [ 25 ], Mozambique [ 57 ], and Zimbabwe [ 58 ] are represented by 01 studies. Regarding study design, 13 studies employed retrospective cohort [ 12 , 14 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 56 , 57 ], whereas 07 prospective cohort studies [ 31 , 32 , 46 , 47 , 48 , 49 , 50 ], 01 case-control type [ 36 ], and 11 cross-sectional design [ 24 , 25 , 33 , 34 , 35 , 51 , 52 , 53 , 54 , 55 , 58 ]. All studies included in this review were observational studies which were conducted in the hospital with sample sizes ranging from 100 participants reported from a study in Ethiopia and Sudan [ 25 , 36 ], and 29811 from Uganda [ 12 ] respectively ( Table 1 ).…”

Section: Resultsmentioning

confidence: 99%

Impact of respiratory distress syndrome and birth asphyxia exposure on the survival of preterm neonates in East Africa continent: systematic review and meta-analysis

Chanie

Alemu

Mekonen

et al. 2021

Heliyon

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Introduction: Several kinds of researches are available on preterm mortality in the East Africa continent; however, it is inconsistent and inconclusive, which requires the pooled evidence to recognize the burden in general. Purpose: To collect and synthesis evidence on preterm mortality and identify factors in the East Africa continent. Methods: PubMed, Google Scholar, Hinary, Cochrane library, research gate, and institutional repositories were retrieved to identity eligible articles through Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. The articles were selected if the publication period is between 2010-2021 G.C. Data were extracted by a standardized JBI data extraction format for mortality rate and stratified the associated factors. Then exported to STATA 14 for further analysis. I 2 and Egger's tests were employed to estimate the heterogeneity and publication bias respectively. Subgroup analysis based on country, study design, year of publication, and the sample size was also examined. Result: This meta-analysis included 32 articles with a total of 21,405 study participants. The pooled mortality rate among preterm in the East Africa continent was found to be 19.2% (95% CI (confidence interval (16.0-22.4)). Regarding the study design, the mortality rate was found to be 18.1%, 19.4%, and 19.7% concerning the prospective cohort, retrospective cohort, and cross-sectional studies. The pooled odds of mortality among preterm with respiratory distress syndrome decreased survival by nearly three folds [AOR (Adjusted odds ratio ¼ 3.2; 95% CI: 22, 4.6)] as compared to their counterparts. Similarly, preterm neonates presented with birth asphyxia were nearly three times higher in death as compared with preterm without birth asphyxia [AOR ¼ 2.6; 95% CI: 1.9, 3.4]. Conclusion: Preterm mortality was found to be unacceptably high in Eastern Africa continent. Fortunately, the main causes of death were found to be respiratory distress syndrome and birth asphyxia which are preventable and treatable hence early detection and timely management of this problem are highly recommended to improve preterm survival.

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“…Data were gathered using a pretested interviewer-administered questionnaire based on pertinent literature 10 13–22. The questionnaire was prepared in English and translated into Amharic and then retranslated into English by senior experts.…”

Section: Methodsmentioning

confidence: 99%

Survival status and predictors of mortality among preterm neonates admitted in Bench Sheko Zone, Sheka Zone and Keffa Zone Governmental Hospitals, Southwest Ethiopia (2021): prospective follow-up study

Mihretu,

Genie,

Adugnaw

et al. 2024

BMJ Open

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IntroductionPrematurity presents a significant challenge to the global community due to the rapid increase in its incidence and its disproportionate contribution to increased infant mortality rates.ObjectiveTo assess the survival status and predictors of mortality among preterm neonates.DesignA multicentre prospective follow-up study was used.Setting625 preterm neonates were admitted to hospitals for secondary level of care. The study covers the Bench Maji Zone, Keffa Zone, Sheka Zone, nearby woredas and portions of the Gambella area in Southwest Ethiopia.Participants614 preterm neonates with gestational age less than 37 weeks were entered for follow-up and 400 neonates were censored. Neonates with severe fetal malformations and neonates who need urgent referral were excluded from the study.ResultsOverall, 200 (32.57%) participants died with an incidence rate of 61.69 deaths per 1000 person-day observations (95% CI: 53.71 to 70.86). Poor kangaroo mother care (KMC) services (adjusted HR (AHR)=0.19, 95% CI: 0.12 to 0.29), sex (AHR=0.66, 95%, CI: 0.47 to 0.94), not initiating breast feeding (HR=2.78, 95% CI: 1.8 to 4.28), hypothermia (AHR=0.63, 95% CI: 0.44 to 0.92), anaemia (AHR=6.2, 95% CI: 2.34 to 16.43) and gestational age less than 28 weeks (AHR=9.28, 95% CI: 1.78 to 48.42) were independent predictors.Conclusion and recommendationThe rate of preterm neonatal mortality was high compared with the Ethiopia Demographic and Health Survey report nationally. Healthcare workers should encourage KMC services and breastfeeding initiation and prevent preterm neonates from being anaemic to increase their chances of survival.

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Survival time and its predictors among preterms in the neonatal period post-discharge in Busoga region-Uganda June – July 2017

Cited by 7 publications

References 19 publications

Escalating the limit of median survival time and predictors of mortality among preterm neonates in Northwest Ethiopia, 2021: a 1-year prospective follow-up study

Escalating the limit of median survival time and predictors of mortality among preterm neonates in Northwest Ethiopia, 2021: a 1-year prospective follow-up study

Impact of respiratory distress syndrome and birth asphyxia exposure on the survival of preterm neonates in East Africa continent: systematic review and meta-analysis

Survival status and predictors of mortality among preterm neonates admitted in Bench Sheko Zone, Sheka Zone and Keffa Zone Governmental Hospitals, Southwest Ethiopia (2021): prospective follow-up study

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