Survival of Patients in Clinical Stages I–IIIb of Non-Small-Cell Lung Cancer Treated with Radiation Therapy Alone

Abstract

Patients treated with 50 to < 60 Gy under a potentially curative therapeutic regimen had a significantly lower survival, compared to patients treated with >/= 60 Gy. In terms of quality assurance, the large proportion of patients treated with radiation doses below the curative range of >/= 60 Gy was unexpected.

6-Year Experience of Concurrent Radiochemotherapy with Vinorelbine Plus a Platinum Compound in Multimorbid or Aged Patients with Inoperable Non-Small Cell Lung Cancer

“…These data enter into the broad spectrum of results on concurrent RCT [13,15]. Based on all data in the aggregate concurrent RCT provides better results that radiotherapy alone with a median survival of 9 months [1,11]. …”

Photons or Protons: Precision Radiotherapy of Lung Cancer

“…In conventional radiotherapy dose escalation has been proved to achieve better tumor control and survival, but it is limited by higher toxicity to the normal tissue [2,4]. For small early-stage peripheral tumors hypofractionated stereotactic radiotherapy has shown an important improvement of clinical results in comparison with 3D-CRT.…”

Thermoplastic Patient Fixation

“…However, due to the side effects, the radiation dose is limited by the volume of the normal tissues. If uncertainties resulting from tumor motions will not be considered when performing PTV delineation, this involves the risk that the CTV cannot be covered as required, and consequently, the delivery of an adequate tumor-destroying dose becomes doubtful [2,4,8].…”

“…In the treatment of the disease, surgery, radiotherapy and chemotherapy play an important role [1,4,9,10]. Radiotherapy and chemotherapy are often used as a combined modality, like in a variety of different tumors [5,19,38].…”