Survival of neonates and predictors of their mortality in Tigray region, Northern Ethiopia: prospective cohort study

Mengesha, Hayelom Gebrekirstos; Wuneh, Alem Desta; Lerebo, Wondwossen; Tekle, Tesfay Hailu

doi:10.1186/s12884-016-0994-9

Cited by 97 publications

(157 citation statements)

References 30 publications

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“…The mortality rate of premature infants born at home is five times as high as those at the same hospital supported by studies conducted in Johannesburg, South Africa [18,28] and Jimma, Ethiopia [8].…”

Section: Discussionmentioning

confidence: 97%

“…Studies reported that preterm neonatal mortality in Ethiopia there is regional variation 28.28% University of Gondar [7], Tigray region Northern Ethiopia 34% [8], and Jimma University Specialized Hospital, Ethiopia 34.9% [9], 47% rural Ethiopia [10], 63% Northern Ethiopia [11]. According to different kinds of literature, factors that are associated with preterm neonatal mortality include;…”

Section: Introductionmentioning

confidence: 99%

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Proportion And Factors Of Death Among Preterm Neonates Admitted In Aksum University Compressive Specialized Hospital Neonatal Intensive Care Unit Northern Ethiopia 2019.

Gebremeskel¹,

Mamo²,

Berhe³

2020

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Section: Discussionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

Proportion And Factors Of Death Among Preterm Neonates Admitted In Aksum University Compressive Specialized Hospital Neonatal Intensive Care Unit Northern Ethiopia 2019.

Gebremeskel¹,

Mamo²,

Berhe³

2020

Preprint

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“…The study included 1162 mother-neonate dyads. Details of sample size calculation and sampling procedure have been published previously [20]. …”

Section: Methodsmentioning

confidence: 99%

“…Clinical characteristics related to the mother and her baby were either extracted from medical record or collected at baseline. Details of follow up have been published previously [20]. …”

Section: Methodsmentioning

confidence: 99%

Cause of neonatal deaths in Northern Ethiopia: a prospective cohort study

2017

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BackgroundDespite the significant reduction in childhood mortality, neonatal mortality has shown little or no concomitant decline worldwide. The dilemma arises in that the lack of documentation of cause of death in developing countries, where registration of vital events is virtually nonexistent. Understanding of the causes of death in neonates is important to guide public health interventions. The present study identifies the common causes of neonatal death in Ethiopia.MethodsA prospective cohort study was conducted among neonates born between April 2014 and July 2014 in seven hospitals, in Tigray region, Ethiopia. Mothers were interviewed by midwifes respecting risk factors and infant survival. For neonates who died in hospital, causes of death were extracted from medical records, whereas a verbal autopsy method provided presumptive assignment of cause of death for those infants who died at home.ResultsOf the1152 live births, there were 68 deaths (63 per 1000 live births). Two thirds of deaths were attributable to prematurity 23 (34%) or asphyxia 21 (31%). Slight variance was seen between the morality patterns in early and late neonatal periods. In the early neonatal period, 37% were due to prematurity, while asphyxia (35%) was more common in the late neonatal period. All infection-related deaths occurred in neonate-mother dyads from rural areas.ConclusionPrematurity, asphyxia, and infections were the leading causes of neonatal deaths in Tigray region during the study period. Causes of deaths identified during early and late neonatal mortality differed, which clearly indicates the need for responsive and evidence-based interventions and policies.

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“…To assess the association of neonatal sepsis with neonatal mortality, we have include five studies [33,[36][37][38]41], Patients who had neonatal sepsis had almost one and half times higher chance of neonatal death compared to those patients without sepsis OR: 1.23(95% CI:1.1, 1.4) ( Figure 7). The heterogeneity test showed extreme evidence of variation across studies (I 2 = 90%, P=…”

Section: Neonatal Sepsismentioning

confidence: 99%

The magnitude of neonatal mortality and its predictors in Ethiopia: a systematic review and meta-analysis

Asmare

Shibabaw

Akalu

et al. 2019

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AbstractsBackground: Although neonatal death is a global burden, it is the highest in Sub Saharan Africa countries such as Ethiopia. This study was aimed to provide pooled national prevalence and predictors of neonatal mortality in Ethiopia. Objective:To assess the pooled prevalence and predictors of neonatal mortality in Ethiopia.Search Strategy: global databases were systematically explored. Systematically searched using the following databases: Boolean operator, Cochrane library, PubMed, EMBASE, HINARI, and Google Scholar. Selection, screening, reviewing and data extraction was done by two reviewers independently using Microsoft excel spread sheet. The modified Newcastle-Ottawa Scale (NOS) and the Joanna Briggs Institute Prevalence Critical Appraisal tools were used to assess the quality of evidence Selection criteria: All studies conducted in Ethiopia and reporting the prevalence and predictors of neonatal mortality were included Data Collection and Analysis: Data were extracted using a Microsoft Excel spreadsheet software and imported into STATA Version 14 s for further analysis. The pooled effect size with 95% confidence interval of neonatal mortality rate was determined using a weighted inverse variance random-effects model. Publication bias was checked using funnel plots, Egger's and bagger's regression test. Heterogeneity also checked by Higgins's method. A random effects meta-analysis model was computed to estimate the pooled effect size (i.e. prevalence and odds ratio). Moreover, subgroup analysis based on region, sample size and study design were done. Results:After reviewing 88 studies, 12 studies fulfilled the inclusion criteria and were included in the meta-analysis. The pooled national prevalence of neonatal mortality in Ethiopia was 16.3% (95% CI: 11.9, 20.7, I 2 =88.6%). The subgroup analysis indicated that the highest prevalence was observed in Amhara region with a prevalence of 20.3% (95% CI: 9.6, 31.1, I 2 =98.8) followed by Oromia, 18.8% (95%CI: 11.9,49.4, I 2 =99.5). Gestational age AOR,1.14 (95% CI: 0.94 ,1.3), neonatal sepsis (OR:1.2(95% CI: 0.8, 1.5), respiratory distros (OR: 1.2(95% CI: 0.8, 1.5) and place of residency (OR:1.93 (95% CI:1.1,2.7) were the most important predictor.Conclusions: neonatal mortality in Ethiopia was significantly decreased than the national report.There was evidence that neonatal sepsis, gestational age, respiratory distress were the significant predictors. We strongly recommended that health care workers should give a priority for the identified predictors.

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Survival of neonates and predictors of their mortality in Tigray region, Northern Ethiopia: prospective cohort study

Cited by 97 publications

References 30 publications

Proportion And Factors Of Death Among Preterm Neonates Admitted In Aksum University Compressive Specialized Hospital Neonatal Intensive Care Unit Northern Ethiopia 2019.

Proportion And Factors Of Death Among Preterm Neonates Admitted In Aksum University Compressive Specialized Hospital Neonatal Intensive Care Unit Northern Ethiopia 2019.

Cause of neonatal deaths in Northern Ethiopia: a prospective cohort study

The magnitude of neonatal mortality and its predictors in Ethiopia: a systematic review and meta-analysis

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