Survival and prognosis of women with invasive cervical cancer according to age

Brun, Jean Luc; Stoven-Camou, Dorothée; Trouette, R.; Lopez, Malika; Chêne, Geneviève; Hocké, C.

doi:10.1016/s0090-8258(03)00501-8

Cited by 47 publications

(30 citation statements)

References 20 publications

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“…Other Asian countries such as Hong Kong, Singapore and South Korea have their overall survival rate higher than 65% (National Cancer Institute, 2013). Our findings also showed that Malaysian overall survival rate is at par with other developed countries such as France which has the overall survival rate of cervical cancer at 70% as reported by Brun et al, (2003). Other developed countries such as the United States, Australia and Japan have their 5-year survival rate at 73.3%, 73.6, and 71.5% respectively (Romus et al, 2013).…”

Section: Discussionsupporting

confidence: 69%

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Survival Rates of Cervical Cancer Patients in Malaysia

Muhamad¹,

Kamaluddin²,

Adon³

et al. 2015

Asian Pacific Journal of Cancer Prevention

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Cervical cancer is the most common malignant cancer of the female reproductive organs worldwide. Currently, cervical cancer can be prevented by vaccination and detected at an early stage via various screening methods. Malaysia, as a developing country faces a heavy disease burden of cervical cancer as it is the second most common cancer among Malaysian women. This population based study was carried out to fulfil the primary aim of determining the survival rates of Malaysian women with cervical cancer and associated factors. Data were obtained from two different sources namely, the Malaysian National Cancer Registry (MNCR) and National Health Informatics Centre (NHIC) from 1st January 2000 to 31st December 2005. Kaplan Meier analyses were conducted to identify the overall survival rates and median survival time. Differences in survival among different ethnic and age group were compared using the log-rank test. A total of 5,859 patients were included. The median survival time for cervical cancer in this study was 65.8 months and the 5-year survival rate was 71.1% . The overall observed survival rates at 1, 3 and 5 years were 94.1%, 79.3% and 71.1% respectively. The log-rank test finding also showed that there were significant differences in the 5-year survival rate among different ethnic groups. Malays had the lowest survival rate of 59.2% followed by Indians (69.5%) and Chinese (73.8%). The overall 5-year survival rate among patients with cervical cancer in Malaysia is relatively good. Age and ethnic groups remain as significant determining factors for cervical cancer survival rate.

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Section: Discussionsupporting

confidence: 69%

“…Brun et al, (2003) reported that the patient's age, one of the minor risk factor, play an important role in cervical cancer survival. This study showed that about 65% of individuals were between 45 years old and above.…”

Section: Discussionmentioning

confidence: 99%

Survival Rates of Cervical Cancer Patients in Malaysia

Muhamad¹,

Kamaluddin²,

Adon³

et al. 2015

Asian Pacific Journal of Cancer Prevention

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“…Garipagaoglu et al (1999) claimed that the survival difference was not statistically significant due to a very small number of patients in younger age group (< 40 years). In contrast, Brun et al (2003) reported opposite finding. It was identified that the percentage of younger patients was large in their study.…”

Section: Discussionmentioning

confidence: 84%

“…On the other hand, our finding was low compared to the overall five-year survival in other countries in Asia such as Hong Kong, the Republic of Korea and Singapore where the overall survival exceeded 65% . In a study in France, Brun et al (2003) found that the five-year survival was 70%. The result was higher than our study's finding might be due to high percentage of younger patients was included in their study.…”

Section: Discussionmentioning

confidence: 96%

Estimating the Five-Year Survival of Cervical Cancer Patients Treated in Hospital Universiti Sains Malaysia

Razak

Khattak²,

Zubairi³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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“…Brun et al investigated the survival of 308 women with invasive cervical cancer and reported that clinical vaginal involvement was an independent prognostic factor along with the prognostic factors of age, gross cervical appearance, histologic grade, and microscopic cervical and parametrial involvement 50) . The overall 5-year survival rates at our institution were 94.3% and 40.1% in patients with negative and positive clinical vaginal involvement, respectively.…”

Section: Resultsmentioning

confidence: 99%

Retrospective Investigation of Patients with Cervical Cancer and its Prognostic Factors

et al. 2005

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Background : The purpose of this study were to investigate the survival rate of patients with cervical cancer who were treated at our institution and to analyse its prognostic factors. Methods : One hundred twenty-two patients who underwent treatment for primary cervical cancer at Kochi Municipal Hospital between January 1996 and August 2003 (7 years 8 months) were retrospectively reviewed. There were 59 patients (48.4%) with stage 0 disease. Sixty-three patients (51.6%) had stage I-IV cervical cancer. The mean age was 56.7±15.6 years, and the median follow-up period was 31 months. Results : The overall 5-year suvival rate was 96.4% and 77.1% in stage I and II, respectively. The overall 3-year survival rate was 56.3% in stage III, and the 30-month survival rate was 0% in stage IV. Among the risk factors of histologic cell type, clinical parametrial involvement, clinical vaginal involvement and pelvic lymph node metastasis , clinical parametrial involvement had the lowest p value (p=0.0717) in a multivariate Cox proportional hazards regression analysis.Multivariate analysis using the Cox proportional hazard regression model showed that among the risk factors of histologic cell type, clinical parametrial involvement, clinical vaginal involvement and pelvic lymph mode metastasts, the lowest p value (p=0.0717) was for clinical parametrial involvement. Conclusion : Although there was no statistical significance comparing the prognostic factors in multivariate analysis, it was presumed that clinical parametrial involvement was the most influential factor among those which were analyzed in this study on the prognosis of patients with stage I-IV cervical cancer.Key words : cervical cancer, prognosis, prognostic factors Cervical cancer is second only to breast cancer as the most common female malignancy in both incidence and mortality worldwide 1)

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Survival and prognosis of women with invasive cervical cancer according to age

Cited by 47 publications

References 20 publications

Survival Rates of Cervical Cancer Patients in Malaysia

Survival Rates of Cervical Cancer Patients in Malaysia

Estimating the Five-Year Survival of Cervical Cancer Patients Treated in Hospital Universiti Sains Malaysia

Retrospective Investigation of Patients with Cervical Cancer and its Prognostic Factors

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