Survival and cardiovascular events after coarctation-repair in long-term follow-up (COAFU): Predictive value of clinical variables

Heck, Pinar Bambul; Ohain, Jelena Pabst von; Kaemmerer, Harald; Ewert, Peter; Hager, Alfred

doi:10.1016/j.ijcard.2016.11.164

Cited by 32 publications

(14 citation statements)

References 23 publications

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“…In this setting with a well‐developed antenatal screening programme, the anomalies that continue to pose diagnostic challenges in the fetus are also those known to have excellent post‐intervention survival . There should be ongoing efforts to improve antenatal detection of CHD.…”

Section: Discussionmentioning

confidence: 99%

Newborn pulse oximetry screening in the context of a high antenatal detection rate of critical congenital heart disease

et al. 2019

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Aim Assess the potential additional benefit from pulse oximetry screening in the early detection of critical congenital heart disease in a country with a well‐developed antenatal ultrasound screening programme. Methods Live‐born infants, pregnancy terminations and stillbirths from 20 weeks’ gestational age, between 2013 and 2015, with critical cardiac defects defined as primary or secondary targets of pulse oximetry screening were identified. Critical defects were those resulting in the death of a fetus or an infant in the first 28 days after birth, or a defect requiring intervention in the first 28 days. Results Two hundred and sixty‐eight infants and Fetuses were identified. Antenatal detection rates improved from 69% to 77% over the study period. An associated co‐morbidity improved antenatal detection rates. Twenty‐seven live‐born infants were diagnosed after discharge: 15 aortic arch obstruction (AAO); 10 d‐loop transposition of the great arteries (d‐TGA), and two total anomalous pulmonary venous drainage (TAPVD). Of these, five with AAO, nine with d‐TGA and likely both with TAPVD could potentially have been detected with oximetry screening. Conclusion The antenatal detection of critical cardiac anomalies continues to improve in New Zealand. Despite high antenatal detection rates for most lesions, universal postnatal oximetry screening has the potential to improve early detection.

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Section: Discussionmentioning

confidence: 99%

Newborn pulse oximetry screening in the context of a high antenatal detection rate of critical congenital heart disease

et al. 2019

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“…Aortic coarctation is common in Turner syndrome and is frequently found in individuals who also have BAV and arch anomalies. Coarctation is associated with an increased likelihood of aortic dilation and dissection (Bambul Heck, Pabst von Ohain, Kaemmerer, Ewert, & Hager, ; Cools, Brown, & Gewillig, ; Eckhauser et al, ). Hypertension, a common consequence of aortic coarctation that may manifest in childhood, and altered compliance or distensibility of the aorta, which is prevalent in patients with coarctation, may both contribute to aortic disease (Hjerrild et al, ; Pees et al, ; Schoepp et al, ; Wen et al, ).…”

Section: Cardiovascular Health Issuesmentioning

confidence: 99%

Recognition and management of adults with Turner syndrome: From the transition of adolescence through the senior years

Lin

Prakash

Andersen

et al. 2019

American J of Med Genetics Pt A

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Turner syndrome is recognized now as a syndrome familiar not only to pediatricians and pediatric specialists, medical geneticists, adult endocrinologists, and cardiologists, but also increasingly to primary care providers, internal medicine specialists, obstetricians, and reproductive medicine specialists. In addition, the care of women with Turner syndrome may involve social services, and various educational and neuropsychologic therapies. This article focuses on the recognition and management of Turner syndrome

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“…Coarctation of the aorta (CoA) is a type of congenital heart disease characterised by stenosis in the aorta, typically juxta-ductal. The incidence is 1 in 2000 live births,1–3 representing 5%–8% of the congenital cardiovascular malformations 1–6. It can occur with other congenital lesions, most commonly bicuspid aortic valve (BAV) and ventricular septum defect 2 3…”

Section: Introductionmentioning

confidence: 99%

Echocardiography during submaximal isometric exercise in children with repaired coarctation of the aorta compared with controls

et al. 2019

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ObjectivePatients with repaired coarctation (RCoA) remain at higher risk of cardiac dysfunction, initially often only detected during exercise. In this study, haemodynamics of isometric handgrip (HG) and bicycle ergometry (BE) were compared in patients with RCoA and matched controls (MCs).MethodsCase–control study of 19 children with RCoA (mean age 12.9±2.3 years; mean age of repair 7 months) compared with 20 MC. HG with echocardiography followed by BE was performed in both groups.ResultsDuring HG (blood pressure) BP increased from 114±11/64±4 mm Hg to 132±14/79±7 mm Hg, without significant differences. During HG as well as BE, HR increased less in patients with RCoA. There were no significant differences in (left ventricle) LV dimensions or LV mass.The RCoA group had diastolic dysfunction: both at rest and during HG they had significantly higher transmitral E and A velocities and lower tissue Doppler E′ and A′ velocities. E/E′ was higher, reaching statistical significance during HG (p<0001).Conventional parameters of systolic function (FS and EF) were similar at rest and HG. More sensitive tissue Doppler S′ was significantly lower at rest in CoA subjects (5.1±1.5 cm/s vs 6.5±1±1 cm/s; p<0.01), decreasing further during HG by 5% in the CoA group (NS) while unchanged in controls.ConclusionsWe provide first evidence that HG with echocardiography is feasible, easy and patient-friendly. A decreased systolic (tissue Doppler) and impaired diastolic LV function was measured in the RCoA group, a difference that tended to increase during HG.

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Survival and cardiovascular events after coarctation-repair in long-term follow-up (COAFU): Predictive value of clinical variables

Cited by 32 publications

References 23 publications

Newborn pulse oximetry screening in the context of a high antenatal detection rate of critical congenital heart disease

Newborn pulse oximetry screening in the context of a high antenatal detection rate of critical congenital heart disease

Recognition and management of adults with Turner syndrome: From the transition of adolescence through the senior years

Echocardiography during submaximal isometric exercise in children with repaired coarctation of the aorta compared with controls

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