Survival analysis of patients with stage IV gastric cancer following palliative surgery based on inflammation-based prognostic score

Abstract

Objective: The Glasgow Prognostic Score (GPS) has been demonstrated to be a useful prognostic factor for various tumors. The aim of the current study was to clarify the significance of the GPS for predicting postoperative survival of patients with stage IV gastric cancer after receiving palliative surgery. Summary of background data:Generally stage IV gastric cancer is not considered for curative surgery. However, palliative surgery is often required to improve the quality of life of patients.Methods: 51 consecutive patients with stage IV gastric cancer was performed the association between GPS, clinicopathological factors and overall survival was assessed.Results: Peritoneal lavage cytology (CY), P0CY1 (no peritoneal dissemination and CY positive), surgical treatment, operative time and curability factors were correlated well with the GPS score. The number of metastatic sites (1 vs. ≧2), curability (R0, R1 vs. R2) and GPS score (0, 1 vs. 2) were found to be the independent prognostic factor. The prognosis of patients with a high GPS was significantly poor. Conclusion:In patients with a GPS of 2, surgical treatment offered only few benefits to the patients and, thus, less invasive treatment should be recommended for these patients.

Survival of Gastric Cancer Patients at a Tertiary Care Hospital in Eastern India: A Retrospective Data Analysis

“…Our study had several limitations. Being a retrospective study [ 19 , 20 ], the inherent bias (incidence-prevalence bias) cannot be excluded, and because it was a single institution, hospital-based study, generalization to the entire population would be difficult. Although the five-year survival is a standard method of representation, due to a lack of available data, we have only presented two-year survival.…”