Survival After Surgery for Pathologic Stage IA Non-Small Cell Lung Cancer Associated With Idiopathic Pulmonary Fibrosis

Impact of Pretreatment Interstitial Lung Disease on Radiation Pneumonitis and Survival after Stereotactic Body Radiation Therapy for Lung Cancer

“…In surgically treated patients, the rates of death due to respiratory failure were increased in patients with ILD, but not primary cancer death. 20,45 The response to chemotherapy was reported to be identical in those with and without ILD. 44 These results suggest that the poor prognosis in ILD(+) patients after treatment should be ascribed to the ILD itself.…”

Surgical Outcomes of Lung Cancer Patients with Combined Pulmonary Fibrosis and Emphysema and Those with Idiopathic Pulmonary Fibrosis without Emphysema

“…Previous studies [20][21][22][23][24][25] reported that postoperative respiratory complications were found in 26%-54.0% of patients with IPF, moderately higher than in the present study, in which the CPFE group had a significantly higher rate of cardiopulmonary morbidity than the IPF alone group; this was assumed to be due to the fact that postoperative PFT decreased unexpectedly in CPFE, involving both %VC and FEV1%, because the CPFE patients experienced AE at almost the same rate as IPF patients without emphysema and required more HOT than IPF patients without emphysema. Moreover, previous studies 7,9,10,14) noted that CPFE was highly associated with pulmonary hypertension, which might be regarded as a cause of more 19) reported that postoperative pulmonary complications occurred in 20% of CPFE patients.…”

Comorbidities in idiopathic pulmonary fibrosis patients: a systematic literature review

“…In patients who received surgical treatment for lung cancer, post-operative mortality (e.g. 30-day, 90-day, in-hospital) tended to be low (0 deaths [95,96], 4% [96,97], 5% [98], 7% [97], 8% [98,99], 12% [93,98]), although a small database review from China reported a post-operative mortality rate of 33.3% (two of six patients) [84]. Median survival from IPF diagnosis was between 7 (95% CI 2.51-11.49) and 26.9 months (95% CI 14.67-39.05) [84,89].…”

“…arrhythmia and atrial fibrillation [26,28,48,75,96,117,118] figure 12) and weight disorders [10,23,26,125,131,134,137] (online supplementary table S14)) among patients with IPF. IHD was the most frequently reported cardiovascular comorbidity (reported in 24 papers).…”