Survey of the patients with cleft lip and palate in China who were funded for surgery by the Smile Train Program from 2000 to 2002

Zhou, Qin‐Mei; Shi, Bing; Shi, Zong-dao; Zheng, Qian; Wang, Yan

doi:10.1097/00029330-200610020-00005

Cited by 31 publications

(41 citation statements)

References 8 publications

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“…There is a male preponderance in our audit as most of the surgeries were cleft lip, which is more common in males and palate, which is more common in females. [4910] We found no correlation between sex and occurrence of critical incidence.…”

Section: Discussionmentioning

confidence: 64%

A retrospective analysis of anesthetic experience in 2917 patients posted for cleft lip and palate repair

et al. 2013

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Context:Anaesthesia during cleft lip and palate surgery carries a high risk and difficult airway management in children.Aim:to study the perioperative anesthetic complications in poor children with cleft abnormalities.Settings and Design:Retrospective analysis.Materials and Methods:This retrospective audit was conducted on 2917 patients of smile train project under going general anesthesia for cleft lip and palate from January 2007 to December 2010. Demographic, pre-anesthetic status, anesthetic management and anesthesia complications were recorded. Chi-square test was used to assess the relation between patient factors and occurrence of complications.Results:Of the 3044, we were able to procure complete data of 2917 patients. Most of children presented with anemia 251 (35%), 202 (29%) had eosinophilia while 184 (26%) had upper respiratory tract infection. The incidence of perioperative complications was 8.19% of which 33.7% critical incidents occurred during the induction time. The most common complication was laryngospasm 77 (40.9%) followed by difficult intubation 64 (30.9%). There was no mortality.Conclusion:Since these procedures do not characterize an emergency, most of the perioperative complications can be prevented by following the routine installed by the institute and smile train protocols.

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Section: Discussionmentioning

confidence: 64%

A retrospective analysis of anesthetic experience in 2917 patients posted for cleft lip and palate repair

et al. 2013

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“…Seasonal variation for African births with clefts was found that might reflect other maternal complicating factors including nutritional variation and infectious exposures. Seasonal variation in the birth of patients born with clefts of the lip and/or palate was also seen both by a study in Zambia [11] as well by Smile Train’s data from China [12]. In Zambia, births of cleft patients were shown to peak in April and May, with more births from March through August (57.2%) (Table 4) [11].…”

Section: Discussionmentioning

confidence: 75%

Ten-year experience of more than 35,000 orofacial clefts in Africa

et al. 2015

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BackgroundSurgical correction of orofacial clefts greatly mitigates negative outcomes. However, access to reconstructive surgery is limited in developing countries. The present study reviews epidemiological data from a single charitable organization, Smile Train, with a database of surgical cases from 33 African countries from 2001–2011.MethodsDemographic and clinical patient data were collected from questionnaires completed by the participating surgeons. These data were recorded in Excel, analyzed using SPSS and compared with previously reported data.ResultsQuestionnaires were completed for 36,384 patients by 389 African surgeons. The distribution of clefts was: 34.44% clefts of the lip (CL), 58.87% clefts of the lip and palate (CLP), and 6.69% clefts of the palate only (CP). The male to female ratio was 1.46:1, and the unilateral: bilateral ratio 2.93:1, with left-sided predominance 1.69:1. Associated anomalies were found in 4.18% of patients. The most frequent surgeries included primary lip/nose repairs, unilateral (68.36%) and bilateral (11.84%). There was seasonal variation in the frequency of oral cleft births with the highest in January and lowest by December. The average age at surgery was 9.34 years and increased in countries with lower gross domestic products. The average hospital stay was 4.5 days. The reported complication rate was 1.92%.ConclusionsWith the exception of cleft palates, results follow trends of worldwide epidemiologic reports of 25% CL, 50% CLP, and 25% CP, 2:1 unilateral:bilateral and left:right ratios, and male predominance. Fewer than expected patients, especially females, presented with isolated cleft palates, suggesting that limitations in economic resources and cultural aesthetics of the obvious lip deformity may outweigh functional concerns and access to treatment for females. A fewer than expected associated anomalies suggests either true ethnic variation, or that more severely-affected patients are not presenting for treatment. The epidemiology of orofacial clefting in Africa has been difficult to assess due to the diversity of the continent and the considerable variation among study designs. The large sample size of the data collected provides a basis for further study of the epidemiology of orofacial clefting in Africa.Electronic supplementary materialThe online version of this article (doi:10.1186/s12887-015-0328-5) contains supplementary material, which is available to authorized users.

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“…[25] examined 593 patients with cleft lip and palate in Thailand and found female predominance in the cleft palate group. Cleft palate is more common in females in china,[26] Australia,[8] and Glasgow. [27] In a study of 477 cleft palate patients in Jordan, Al-Omari and Al-Omari found that 74% of them were females, confirming the gender variation in cleft palate.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of 22q11.2 deletion in Cleft Palate patients

Prabodha

Dias

Nanayakkara

et al. 2012

Ann Maxillofac Surg

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Background:Cleft palate is the commonest multifactorial epigenetic disorder with a prevalence of 0.43-2.45 per 1000. The objectives of this study were to evaluate the clinical features and identify the 22q11.2 deletion in patients with cleft palate in Sri Lanka.Materials and Methods:Cleft patients attending a Teaching Hospital in Sri Lanka were recruited for this study. The relevant data were obtained from review of case notes, interviews, and examination of patients according to a standard evaluation sheet. Quantitative multiplex polymerase chain reaction (PCR) was performed to identify the 22q11.2 deletion. A gel documentation system (Bio-Doc) was used to quantify the PCR product following electrophoresis on 0.8% agarose gel.Results and Conclusion:There were 162 cleft palate patients of whom 59% were females. A total of 92 cleft palate subjects (56.2%) had other associated clinical features. Dysmorphic features (25.27%) and developmental delays (25.27%) were the commonest medical problems encountered. The cleft was limited to the soft palate in 125 patients, while in 25 patients it involved both the hard and the soft palate. There were seven subjects with bifid uvula and five subjects with submucous cleft palate. None of the patients had 22q11.2 deletion in this study population. A multicentered large population-based study is needed to confirm the results of this study and to develop guidelines on the appropriate use of 22q11.2 deletion testing, which are valid for cleft palate patients in Sri Lanka.

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Survey of the patients with cleft lip and palate in China who were funded for surgery by the Smile Train Program from 2000 to 2002

Cited by 31 publications

References 8 publications

A retrospective analysis of anesthetic experience in 2917 patients posted for cleft lip and palate repair

A retrospective analysis of anesthetic experience in 2917 patients posted for cleft lip and palate repair

Ten-year experience of more than 35,000 orofacial clefts in Africa

Evaluation of 22q11.2 deletion in Cleft Palate patients

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