Survey of distribution of seasonal influenza vaccine doses in 201 countries (2004–2015): The 2003 World Health Assembly resolution on seasonal influenza vaccination coverage and the 2009 influenza pandemic have had very little impact on improving influenza control and pandemic preparedness

Palache, Abraham; Abelin, Atika; Hollingsworth, Rosalind; Cracknell, W.; Jacobs, Choolwe; Tsai, Theodore F.; Barbosa, Patrícia

doi:10.1016/j.vaccine.2017.07.053

Cited by 56 publications

(42 citation statements)

References 18 publications

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“…As of 2016, more than 115 countries had national influenza immunization policies in place [10]. However, recommendations alone do not translate into high vaccine coverage, and most countries, even those with recommendations, still had low influenza vaccine coverage in 2015 [11]. To build public trust and increase influenza vaccine uptake, policy makers and other decision makers need to better understand vaccination coverage and the factors influencing the acceptance of influenza vaccine among different risk groups [12].…”

Section: Introductionmentioning

confidence: 99%

Influenza Vaccination Coverage among Registered Nurses in China during 2017–2018: An Internet Panel Survey

Ren

et al. 2019

Vaccines

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Influenza vaccination is recommended for nurses in China but is not mandatory or offered free of charge. The main objective of this study was to determine influenza vaccination coverage and the principal factors influencing influenza vaccination among nurses in China. During 22 March–1 April 2018, we conducted an opt-in internet panel survey among registered nurses in China. Respondents were recruited from an internet-based training platform for nurses. Among 22,888 nurses invited to participate, 4706 responded, and 4153 were valid respondents. Overall, 257 (6%) nurses reported receiving the seasonal influenza vaccine during the 2017/2018 season. Vaccination coverage was highest among nurses working in Beijing (10%, p < 0.001) and nurses working in primary care (12%, p = 0.023). The top three reasons for not being vaccinated were lack of time (28%), not knowing where and when to get vaccinated (14%), and lack of confidence in the vaccine’s effectiveness (12%). Overall, 41% of nurses reported experiencing at least one episode of influenza-like illness (ILI) during the 2017/2018 season; 87% of nurses kept working while sick, and 25% of nurses reported ever recommending influenza vaccination to patients. Compared with nurses who did not receive influenza vaccination in the 2017/2018 season, nurses who received influenza vaccination were more likely to recommend influenza vaccination to patients (67% vs. 22%, p < 0.001). Influenza vaccination coverage among nurses was low, and only a small proportion recommended influenza vaccine to patients. Our findings highlight the need for a multipronged strategy to increase influenza vaccination among nurses in China.

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Section: Introductionmentioning

confidence: 99%

Influenza Vaccination Coverage among Registered Nurses in China during 2017–2018: An Internet Panel Survey

Ren

et al. 2019

Vaccines

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“…The exact reasons for the low vaccination rates in EMR are not well understood but are multifaceted and include misperceptions and erroneous interpretations of the efficacy and safety of the vaccine, and the threat that influenza poses to health (5)(6)(7)(8). Additionally, the lack of regional capacity for vaccine production and so reliance on imported vaccine supplies may be a hurdle for increasing vaccine availability and distribution (4).…”

mentioning

confidence: 99%

Harnessing the power of advocacy to improve seasonal influenza vaccination coverage in the Eastern Mediterranean Region

Zaraketa

Abubakar

2020

East Mediterr Health J

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“…Influenza virus is the only pathogen that is recommended for yearly vaccination, with over 500 million doses used globally every year. 25 IIV has limited protection against infecting strains that are antigenically distinct from those contained in the vaccine. This can create a public health problem, such as recent H3N2 viruses, which have been more difficult to match and control with S-IIV.…”

Section: Discussionmentioning

confidence: 99%

Assessment of enhanced influenza vaccination finds that FluAd conveys an advantage in mice and older adults

Kavian

Hachim

et al. 2020

Clin & Trans Imm

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Objectives Enhanced inactivated influenza vaccines (eIIV) aim to increase immunogenicity and protection compared with the widely used standard IIV (S‐IIV). Methods We tested four vaccines in parallel, FluZone high dose, FluBlok and FluAd versus S‐IIV in a randomised controlled trial of older adults and in a mouse infection model to assess immunogenicity, protection from lethal challenge and mechanisms of action. Results In older adults, FluAd vaccination stimulated a superior antibody profile, including H3‐HA antibodies that were elevated for up to 1 year after vaccination, higher avidity H3HA IgG and larger HA stem IgG responses. In a mouse model, FluAd also elicited an earlier and larger induction of HA stem antibodies with increased germinal centre responses and upregulation and long‐term expression of B‐cell switch transcription factors. Long‐term cross‐reactive memory responses were sustained by FluAd following lethal heterosubtypic influenza challenge, with reduced lung damage and viral loads, coinciding with increased T‐ and B‐cell recall. Advantages were also noted for the high‐dose FluZone vaccine in both humans and mice. Conclusion The early, broadly reactive and long‐lived antibody response of FluAd indicates a potential advantage of this vaccine, particularly in years when there is a mismatch between the vaccine strain and the circulating strain of influenza viruses.

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Survey of distribution of seasonal influenza vaccine doses in 201 countries (2004–2015): The 2003 World Health Assembly resolution on seasonal influenza vaccination coverage and the 2009 influenza pandemic have had very little impact on improving influenza control and pandemic preparedness

Cited by 56 publications

References 18 publications

Influenza Vaccination Coverage among Registered Nurses in China during 2017–2018: An Internet Panel Survey

Influenza Vaccination Coverage among Registered Nurses in China during 2017–2018: An Internet Panel Survey

Harnessing the power of advocacy to improve seasonal influenza vaccination coverage in the Eastern Mediterranean Region

Assessment of enhanced influenza vaccination finds that FluAd conveys an advantage in mice and older adults

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