over 100 000 people died from an overdose, more than any prior 12-month period. 1 Most overdose deaths involve opioids, predominantly fentanyl analogs. 1 Opioid agonist medications for opioid use disorder (OUD), methadone and buprenorphine, reduce mortality and overdose and improve person-centered outcomes. 2 There are an estimated 2.7 million people with OUD living in the US, and expanding access to buprenorphine is a key component of our national strategy to reduce overdose deaths; however, few people with OUD receive any medication for OUD. 3 Many factors contribute to the low provision of buprenorphine treatment for OUD. 4 A leading factor is the limited availability of buprenorphine prescribers. In 2018, more than 40% of counties in the US did not have any clinicians permitted to prescribe buprenorphine, and more than half of the counties with the greatest treatment need had inadequate treatment capacity. 5 Treatment has expanded during the last decade, but it has been unevenly distributed, and buprenorphine access remains highly restricted, particularly in rural areas and in minoritized racial and ethnic communities. 5,6 To prescribe buprenorphine for OUD, Drug Enforcement Administration (DEA)-licensed physicians, advanced practice nurses (APNs), and physician assistants (PAs) need to apply for an X-waiver from the Substance Abuse and Mental Health Services Administration. 7 Historically, there has been a training requirement to obtain a waiver: 8 hours for physicians and 24 hours for APNs and PAs. As of December 2021, less than 10% of DEA-licensed clinicians were waivered. 8,9 In April 2021, the Biden-Harris administration removed the training requirement to receive a waiver to treat up to 30 patients to expand the number of waivered clinicians, reduce buprenorphine prescribing barriers, and expand buprenorphine access. 10 In this issue of JAMA Network Open, research by Spetz et al 8 and Lanham et al 11 provides important insights into factors influencing buprenorphine prescribing capacity and provision.