Survey of attitudes regarding the use of siblings for gamete donation

Sauer, Mark V.; Rodi, Ingrid A.; Scrooc, Michelle; Bustillo, María; Buster, John E.

doi:10.1016/s0015-0282(16)59847-1

Cited by 47 publications

(14 citation statements)

References 5 publications

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“…This treatment modality has become an important component of the comprehensive assisted fertility treatment programme, and has been available in Ireland for several years. Patient survey results from Irish patients have generally agreed with findings reported elsewhere, showing a strong preference for sister-donor over anonymous-donor oocyte approach in IVF [7]. Although successful sister-donor oocyte IVF has been available in Australia [8] and USA [9] for several years, this is the first description of IVF births resulting from this technique in Ireland.…”

Section: Discussionsupporting

confidence: 80%

IVF for premature ovarian failure: first reported births using oocytes donated from a twin sister

Sills

Brady

Omar³

et al. 2010

Reprod Biol Endocrinol

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BackgroundPremature ovarian failure (POF) remains a clinically challenging entity because in vitro fertilisation (IVF) with donor oocytes is currently the only treatment known to be effective.MethodsA 33 year-old nulligravid patient with a normal karyotype was diagnosed with POF; she had a history of failed fertility treatments and had an elevated serum FSH (42 mIU/ml). Oocytes donated by her dizygotic twin sister were used for IVF. The donor had already completed a successful pregnancy herself and subsequently produced a total of 10 oocytes after a combined FSH/LH superovulation regime. These eggs were fertilised with sperm from the recipient's husband via intracytoplasmic injection and two fresh embryos were transferred to the recipient on day three.ResultsA healthy twin pregnancy resulted from IVF; two boys were delivered by caesarean section at 39 weeks' gestation. Additionally, four embryos were cryopreserved for the recipient's future use. The sister-donor achieved another natural pregnancy six months after oocyte retrieval, resulting in a healthy singleton delivery.ConclusionPOF is believed to affect approximately 1% of reproductive age females, and POF patients with a sister who can be an oocyte donor for IVF are rare. Most such IVF patients will conceive from treatment using oocytes from an anonymous oocyte donor. This is the first report of births following sister-donor oocyte IVF in Ireland. Indeed, while sister-donor IVF has been successfully undertaken by IVF units elsewhere, this is the only known case where oocyte donation involved twin sisters. As with all types of donor gamete therapy, pre-treatment counselling is important in the circumstance of sister oocyte donation.

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Section: Discussionsupporting

confidence: 80%

IVF for premature ovarian failure: first reported births using oocytes donated from a twin sister

Sills

Brady

Omar³

et al. 2010

Reprod Biol Endocrinol

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“…Studies thereafter were carried out predominantly by professionals working in the field of infertility, and argued for the continuation of a particular treatment programme, the ethical acceptability of a specific treatment option or a mode of patient treatment. Articles covered the whole gamut of egg donation types (Sauer et al. 1998, Power et al.…”

Section: Introductionmentioning

confidence: 99%

“…These were predominantly psychological, concentrating on social and psychological characteristics of donor profiles using structured or semi‐structured interviews, often running alongside psychological tests. The remaining two‐thirds were questionnaire‐based (for example: Sauer et al. 1998, Murray et al.…”

Section: Introductionmentioning

confidence: 99%

Exploring the beliefs and experiences of potential egg share donors

Rapport

2003

Journal of Advanced Nursing

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Egg sharing could be seen as a marker of hope. Buoyed up by the possibility of a successful outcome, women are prepared to undertake repetitive treatment attempts despite continued failure to conceive and knowledge of a slim chance of a positive outcome. Implications for practice, policy and ethics result in recommendations for more in-depth interview work by independent researchers to gain a clearer picture of women's responses to reproductive technologies and the development of services in line with patient need and individual expectation.

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“…Some US fertility experts advocated sister-to-sister donation rather than anonymous donation (Lessor, 1993). Studies at that time reported positive attitudes towards egg donation by sisters among infertile couples (Sauer, 1988) and the broader public (Lessor, et al, 1990).…”

Section: Challenges In Intra-family Donation Ejjy Vayena and Susan Gomentioning

confidence: 99%