Surveillance of Microbial Flora for Infertility Couples in an Indian Tertiary Care Teaching Hospital

Abstract

Objective: Infertility has been known to cause serious social and emotional problems in India. Microorganisms may be a primary cause for this infertility. This study was carried out to know the prevalence of microorganisms in the infertility couples of a tertiary caring teaching hospital. Methods:One thousands of couples were screened for the infertility test presented at the outpatient Department of Obstetrics and Gynaecology.The suspected infertility couples were tested for microbial contamination in their reproductive sample. Simultaneously, the demographic data of all patients were documented, and all the data were analyzed with SPSS 20 software.Result: From one thousand couples, 288 couples were found infertility symptoms, whereas 67.71% were primary infertility problems and rest were secondary. It is due to male factor (27.08%), female factor (50%), and both (4.86%) but 18.05 were unexplained. From vaginal swabs, 186 and semen 145 microbial colony were grown. However, Chi-square (χ 2 ) showed that there is no significant difference between the growth of microbial colony from semen or vaginal swap as p=0.06. Eight varieties of bacteria (387) and Candida albicans (37) were documented. Conclusion:With respect to older ages of the infertile couples, it is more chances to infections. Antibiotic should be prescribed to primary infertility couples and infections can be avoided the cross transmission during intercourse.

The Role of Genital Tract Microbiome in Fertility: A Systematic Review

“…An Indian study by Mishra et al [ 26 ] included 288 infertile couples, performing either cervical or high vaginal swab and semen samples for culture analyses. A high prevalence of Escherichia coli was implicated in primary infertility, even though it was not the only isolated pathogen; hence, the authors suggested adopting therapeutic managements strategies of couples with primary infertility such as antibiotics and a parallel treatment to avoid cross-retransmission.…”

Effect of Vaginal Sildenafil on in Vitro Fertilization Success Rates in Women With Previous Failed in Vitro Fertilization Attempts

“…Around one in six or seven couples may have difficulty getting pregnant. Unexplained infertility in addition to common causes of infertility such as ovulation problems, tubal blockage, male associated infertility, uterine problems, and infections are causes which could eventually lead to using associated reproductive technology commonly known as ART in the treatment of infertility [3][4][5][6]. In vitro fertilization (IVF) as a helpful way to treat infertility, particularly fallopian tube and ovarian-related infertility, may lead to failure due to many factors such as female age, embryo quality, ovarian response, or implantation issues.…”