Surround inhibition can instantly be modulated by changing the attentional focus

Kuhn, Yves-Alain; Keller, Martin B.; Lauber, Benedikt; Taube, Wolfgang

doi:10.1038/s41598-017-19077-0

Cited by 42 publications

(46 citation statements)

References 46 publications

(72 reference statements)

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“…In line with this proposal, it has been shown that isometric contractions can be maintained longer when an external focus of attention is adopted (Kuhn et al, 2017a). Interestingly, this improvement of performance was accompanied by an increase in SICI (Kuhn et al, 2017a; Kuhn et al, 2017b) and an increase in surround inhibition (Kuhn et al, 2018).…”

Section: Discussionmentioning

confidence: 99%

Human motor fatigability as evoked by repetitive movements results from a gradual breakdown of surround inhibition

Bächinger

Lehner

Thomas

et al. 2019

eLife

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Motor fatigability emerges when demanding tasks are executed over an extended period of time. Here, we used repetitive low-force movements that cause a gradual reduction in movement speed (or ‘motor slowing’) to study the central component of fatigability in healthy adults. We show that motor slowing is associated with a gradual increase of net excitability in the motor network and, specifically, in primary motor cortex (M1), which results from overall disinhibition. Importantly, we link performance decrements to a breakdown of surround inhibition in M1, which is associated with high coactivation of antagonistic muscle groups. This is consistent with the model that a loss of inhibitory control might broaden the tuning of population vectors such that movement patterns become more variable, ill-timed and effortful. We propose that the release of inhibition in M1 is an important mechanism underpinning motor fatigability and, potentially, also pathological fatigue as frequently observed in patients with brain disorders.

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Section: Discussionmentioning

confidence: 99%

Human motor fatigability as evoked by repetitive movements results from a gradual breakdown of surround inhibition

Bächinger

Lehner

Thomas

et al. 2019

eLife

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“…115 Additionally, engaging in EF increases time to failure, reduces ratings of perceived exertion, 116,117 and increases movement efficiency potentially by reducing unnecessary muscle contributions by modulating the inhibitory mechanisms within the primary motor cortex. 117,118…”

Section: Modified External Focus Of Attention For Visuospatial Attentionmentioning

confidence: 99%

Visual Perturbation to Enhance Return to Sport Rehabilitation after Anterior Cruciate Ligament Injury: A Clinical Commentary

Wohl

Criss

Grooms

2021

International Journal of Sports Physical Therapy

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Anterior cruciate ligament (ACL) tears are common traumatic knee injuries causing joint instability, quadriceps muscle weakness and impaired motor coordination. The neuromuscular consequences of injury are not limited to the joint and surrounding musculature, but may modulate central nervous system reorganization. Neuroimaging data suggest patients with ACL injuries may require greater levels of visual-motor and neurocognitive processing activity to sustain lower limb control relative to healthy matched counterparts. Therapy currently fails to adequately address these nuanced consequences of ACL injury, which likely contributes to impaired neuromuscular control when visually or cognitively challenged and high rates of re-injury. This gap in rehabilitation may be filled by visual perturbation training, which may reweight sensory neural processing toward proprioception and reduce the dependency on vision to perform lower extremity motor tasks and/or increase visuomotor processing efficiency. This clinical commentary details a novel approach to supplement the current standard of care for ACL injury by incorporating stroboscopic glasses with key motor learning principles customized to target visual and cognitive dependence for motor control after ACL injury. Level of Evidence 5

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“…For example, it has been reported that attentional focus (external versus internal) modulates MEPs evoked by motor cortex stimulation (Kuhn et al 2018). Concurrent leg muscle activation results in a prolonged attenuation of EMG activity (i.e.…”

Section: Discussionmentioning

confidence: 99%

Corticospinal correlates of hand preference for reaching during whole-body motion

Wijdenes

Wynn

Roesink

et al. 2021

Preprint

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Behavioral studies have shown that humans account for inertial acceleration in their decisions of hand choice when reaching during body motion. Physiologically, it is unclear at what stage of movement preparation information about body motion is integrated in the process of hand selection. Here, we addressed this question by applying transcranial magnetic stimulation over motor cortex (M1) of human participants who performed a preferential reach task while they were sinusoidally translated on a linear motion platform. If M1 only represents a read-out of the final hand choice, we expect the body motion not to affect the MEP amplitude. If body motion biases the hand selection process prior to target onset, we expect corticospinal excitability to modulate with the phase of the motion, with larger MEP amplitudes for phases that show a bias to using the right hand. Behavioral results replicate our earlier findings of a sinusoidal modulation of hand choice bias with motion phase. MEP amplitudes also show a sinusoidal modulation with motion phase, suggesting that body motion influences corticospinal excitability which may ultimately reflect changes of hand preference. The modulation being present prior to target onset suggests that competition between hands is represented throughout the corticospinal tract. Its phase relationship with the motion profile suggests that other processes after target onset take up time until the hand selection process has been completely resolved, and the reach is initiated. We conclude that the corticospinal correlates of hand preference are modulated by body motion.

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Surround inhibition can instantly be modulated by changing the attentional focus

Cited by 42 publications

References 46 publications

Human motor fatigability as evoked by repetitive movements results from a gradual breakdown of surround inhibition

Human motor fatigability as evoked by repetitive movements results from a gradual breakdown of surround inhibition

Visual Perturbation to Enhance Return to Sport Rehabilitation after Anterior Cruciate Ligament Injury: A Clinical Commentary

Corticospinal correlates of hand preference for reaching during whole-body motion

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