Abstract:Key Points
Percutaneous paravalvular leak (PVL) closure has lower procedure mortality than surgical closure in a non‐randomized comparison
Both percutaneous and surgical PVL closure have high long‐term mortality with nearly half of patients dead after 2.5 years
Multivariate analysis showed age, worse NYHA class, and renal failure were associated with worse prognosis
Earlier detection and treatment of PVL should be considered to improve late results
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