Abstract:Objectives: To examine the surgical treatment and mortality rate of valvular infective endocarditis complicated by an abscess in patients at a major tertiary care center.Background: Infective endocarditis (IE) involving a heart valve is fatal if left untreated. The appearance of a comorbid abscess impacts the choice of treatment and surgical technique and, in some instances, may present unique technical challenges.
“…Post-operative mortality remains high and ranges from 14% to 24%. In-hospital mortality remains same for both cases with culture positive and culture negative IE 15 , 16 . In our case abscess closure, mitral annuloplasty with mitral valve replacement was performed along with 6 weeks of IV antibiotics.…”
IntroductionPerivalvular abscess in native valve infective endocarditis (IE) is associated with significantly increased mortality.Case descriptionHerein, we report a 29 year old Indian male who presented with culture negative IE with perivalvular abscess and severe mitral regurgitation requiring mitral valve replacement.DiscussionInitial approach is very difficult in terms of when IE presents as culture negative. This case highlights the important role of echocardiography in the management of culture negative IE.
“…Post-operative mortality remains high and ranges from 14% to 24%. In-hospital mortality remains same for both cases with culture positive and culture negative IE 15 , 16 . In our case abscess closure, mitral annuloplasty with mitral valve replacement was performed along with 6 weeks of IV antibiotics.…”
IntroductionPerivalvular abscess in native valve infective endocarditis (IE) is associated with significantly increased mortality.Case descriptionHerein, we report a 29 year old Indian male who presented with culture negative IE with perivalvular abscess and severe mitral regurgitation requiring mitral valve replacement.DiscussionInitial approach is very difficult in terms of when IE presents as culture negative. This case highlights the important role of echocardiography in the management of culture negative IE.
“…Valvular perforation may lead to severe valve destruction, intractable heart failure, and even death if timely surgical therapy is not administered[ 11 ]. The presence of an abscess further increases surgical complexity due to excavation of the annular tissue during an ongoing infectious process, making it difficult to perform valve replacement or repair[ 12 ]. Recently, guidelines recommend prolonging the duration of antibiotic treatment for the management of IE[ 1 ].…”
BACKGROUND
Surgical therapy of infective endocarditis (IE) involving aortic valves and mitral valves is widespread. However, there are few reports concerning patients with culture-negative endocarditis complicated by the appearance of comorbid valvular perforation and abscess. Therefore, real-time surveillance of changes in cardiac structure and function is critical for timely surgical management, especially in patients who do not respond to medical therapy.
CASE SUMMARY
Here, we report an atypical case in a 9-mo-old infant without congenital heart disease but with symptoms of intermittent fever and macular rashes. Physical examination, laboratory tests, and electrocardiograms suggested a diagnosis of IE, although the result of blood cultures was exactly negative. After treatment with antibiotic drugs, the patient got a transient recovery. On the 9
th
day, we proceeded with continuous echocardiogram due to fever again and the results revealed aortic valve abscess with perforation, regurgitation, vegetation, and pericardial effusion. Intraoperative monitoring revealed aortic valve perforation, presence of apothegmatic cystic spaces below the left coronary cusp of the aortic valve, and severe aortic valve regurgitation. Aortic valve repair was performed by autologous pericardial patch plasty. The patient was discharged after 4 wk of treatment and no complications occurred after surgery.
CONCLUSION
Our case demonstrated the necessity of serial echocardiography monitoring for possible adverse symptoms of IE in pediatric patients.
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