Surgical treatment of osteogenesis imperfecta: current concepts

Abstract

Recent medical and surgical advances have allowed improved safety, function and comfort in treating children with osteogenesis imperfecta. The selection of surgical techniques is dependent on surgeon experience, severity of disease and patient function, and availability of specific instrumentation. Intramedullary fixation rather than plating is preferred, and allowing early protected weight bearing and rehabilitation of children with ambulatory potential is the ideal goal.

Our Results of Modified Sofield Procedure in Lower Extremity Deformities with Osteogenesis Imperfecta

“…Wilkinson et al [20] reported that these new Sheffield rods result in less epiphyseal damage and has lower rates of complication. Later, it was reported that less joint damage, less invasive procedure, and lower mechanical complications are achieved with the Fassier-Duval nail developed by Fassier and Duval [21]. Besides, these nails have an advantage that removes knee arthrotomy in femoral surgery and ankle arthrotomy in tibial surgery.…”

Cell therapy of a patient with type III <i>osteogenesis imperfecta</i> caused by mutation in <i>COL1A2</i> gene and unstable collagen type I

“…In fact, there is no effective treatment for the patients with OI so far [27][28][29][30]. That is why, it seems to be of crucial importance to continue research studies investigating the role of new methods of therapy in patients with this disease.…”

Intramedullary Elastic Transphyseal Tibial Osteosynthesis and Its Effect on Segmental Growth

“…Это, не-сомненно, оказывает положительное влияние на функци-ональное состояние пациентов, связанное с увеличением их двигательной активности [8,9]. B. Boutaud и J.M.…”