Surgical treatment of morbid obesity among patients with bipolar disorder: a research agenda

Ahmed, Ameena T.; Blair, Thomas R. W.; McIntyre, Roger S.

doi:10.1007/s12325-011-0015-3

Cited by 13 publications

(6 citation statements)

References 92 publications

(51 reference statements)

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“…Only a few absolute psychiatric contraindications of bariatric surgery have been reported, including active psychosis, dementia and active alcohol or other substance use disorders. Interestingly, bariatric surgery has been found to exert a favorable effect on the course and outcome of some psychiatric conditions, such as, bipolar disorder [112], schizophrenia [113], and Prader-Willi Syndrome [114, 115], all of which are associated with obesity.…”

Section: Impact Of Psychopathology On Outcomes Of Bariatric Surgerymentioning

confidence: 99%

Psychopathology in bariatric surgery candidates: A review of studies using structured diagnostic interviews

Malik

Mitchell

Engel

et al. 2014

Comprehensive Psychiatry

115

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Psychiatric disorders are not uncommon among severely obese patients who present for bariatric surgery. This paper (1) reviews the results of the published studies using the structured interviews to assess psychopathology in bariatric surgery candidates; (2) compares the prevalence rates of psychiatric disorders across these studies with the data from other population samples; and (3) assesses whether sociodemographic variables appear to affect these prevalence rates. We searched online resources, PubMed, PsychINFO and reference lists of all the relevant articles to provide an overview of evidence so far and highlight some details in the assessment and comparisons of different samples in different countries. The prevalence estimates in the non- treatment obese group did not appear to differ substantially from the general population group in the US or the Italian population samples, although they were relatively higher for the German population. However, the rates of psychopathology in the bariatric surgery candidates were considerably higher than the other two population groups in all the samples. Overall, the most common category of lifetime Axis I disorders in all the studies was affective disorders, with anxiety disorders being the most common category of current Axis I disorders. Certain demographic characteristics are also associated with higher rates of psychopathology, such as, female gender, low socioeconomic status, higher BMI. Overall, methodological and sociodemographic differences make these studies difficult to compare and these differences should be taken into account when interpreting the results.

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Section: Impact Of Psychopathology On Outcomes Of Bariatric Surgerymentioning

confidence: 99%

Psychopathology in bariatric surgery candidates: A review of studies using structured diagnostic interviews

Malik

Mitchell

Engel

et al. 2014

Comprehensive Psychiatry

115

View full text Add to dashboard Cite

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“…Individuals with bipolar disorder have the highest rates of MetS [17, 19] as well as increased risk for obesity [20] and other metabolic complications [21]. This association is controversial as both typical [22] and atypical [22, 23] antipyschotics are reported to contribute to the increased body weight and MetS.…”

Section: Metabolic Syndrome and Mental Health Comorbiditymentioning

confidence: 99%

Unraveling the Mechanisms Responsible for the Comorbidity between Metabolic Syndrome and Mental Health Disorders

2013

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The increased prevalence and high comorbidity of metabolic syndrome (MetS) and mental health disorders (MHDs) have prompted investigation into the potential contributing mechanisms. There is a bidirectional association between MetS and MHDs including schizophrenia, bipolar disorder, depression, anxiety, attention-deficit/hyperactivity disorder, and autism spectrum disorders. Medication side effects and social repercussions are contributing environmental factors, but there are a number of shared underlying neurological and physiological mechanisms that explain the high comorbidity between these two disorders. Inflammation is a state shared by both disorders, and it contributes to disruptions of neuroregulatory systems (including the serotonergic, dopaminergic, and neuropeptide Y systems) as well as dysregulation of the hypothalamic-pituitary-adrenal axis. MetS in pregnant women also exposes the developing fetal brain to inflammatory factors that predispose the offspring to MetS and psychopathologies. Due to the shared nature of these conditions, treatment should address aspects of both mental health and metabolic disorders. Additionally, interventions that can interrupt the transfer of increased risk of the disorders to the next generation need to be developed.

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“…Cross-sectional and longitudinal studies indicate that obesity, notably morbid obesity, is a medical comorbidity that is significantly more common in adults with MDD and BD when compared to the general population [4][5][6]. The high rate of obesity in mood disorder populations has a complex and heterogeneous aetiology including, but not limited to, a high rate of chaotic eating patterns (e.g., BED).…”

Section: Introductionmentioning

confidence: 99%

Binge eating in adults with mood disorders: Results from the International Mood Disorders Collaborative Project

Woldeyohannes

Soczynska

Maruschak

et al. 2016

Obesity Research & Clinical Practice

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Surgical treatment of morbid obesity among patients with bipolar disorder: a research agenda

Cited by 13 publications

References 92 publications

Psychopathology in bariatric surgery candidates: A review of studies using structured diagnostic interviews

Psychopathology in bariatric surgery candidates: A review of studies using structured diagnostic interviews

Unraveling the Mechanisms Responsible for the Comorbidity between Metabolic Syndrome and Mental Health Disorders

Binge eating in adults with mood disorders: Results from the International Mood Disorders Collaborative Project

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