Surgical treatment of infected thoracic and abdominal aortic aneurysms

Selective medical treatment of infected aneurysms of the aorta in high risk patients

“…In western countries, the most common responsible organisms for infected aortic aneurysms are Staphylococcus aureus and Streptococcus species. [1][2][3][4][5][6][7][8][9][10] In contrast, in Taiwan, nontyphoid Salmonella is the most common pathogen. [14][15][16][17][18][19] It has been reported that aneurysms infected with Gram negative organisms exhibit a greater tendency toward early rupture than those with gram positive organisms and are thus associated with a higher mortality.…”

“…The surgical intervention includes extensive aortic resection and vascular reconstruction. Previous studies have focused mainly on the results of combined medical and open surgical treatment, [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] and there have been almost no hospital survivors if patients were treated medically without undergoing aortic resection. [11][12][13] In this current series of 22 patients treated medically without undergoing aortic resection, the prognosis was not uniformly fatal but the results did not match our reported survival after open surgical repair.…”

“…[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] The successful resolution of these uncommon but not rare aortic lesions relates directly to early diagnosis, administration of specific systemic antibiotics, and timely surgical intervention. The surgical intervention includes extensive aortic resection and vascular reconstruction.…”

“…[1][2][3][4][5][6][7] The hospital mortality rates of combined medical and surgical treatment ranged from 16% to 44%. [1][2][3][4][5][6][7] The clinical outcome is especially poor in patients with infection caused by nontyphoid Salmonella. [8][9][10][11] There were almost no hospital survivors if such patients were treated medically without undergoing aortic resection.…”

“…[1][2][3][4][5][6][7] Early diagnosis, more potent antibiotics, and timely surgical intervention have resulted in improved outcome over the last two decades. [1][2][3][4][5][6][7] The hospital mortality rates of combined medical and surgical treatment ranged from 16% to 44%. [1][2][3][4][5][6][7] The clinical outcome is especially poor in patients with infection caused by nontyphoid Salmonella.…”