2018
DOI: 10.1111/nyas.13677
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Abstract: Over the last decades, the treatment of resectable esophageal cancer has evolved into a multidisciplinary process in which all players are essential for treatment to be successful. Medical oncologists and radiation oncologists have been increasingly involved since the implementation of neoadjuvant therapy, which has been shown to improve survival. Although esophagectomy is still considered the cornerstone of curative treatment for locally advanced esophageal cancer, it remains associated with considerable post… Show more

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Cited by 97 publications
(57 citation statements)
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References 181 publications
(418 reference statements)
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“…Oesophagectomy is the standard for curative management of locally advanced oesophageal cancer. Oesophagectomy is a technically challenging procedure, and is associated with considerable morbidity and mortality despite implementation of minimally invasive techniques.…”
Section: Introductionmentioning
confidence: 99%
“…Oesophagectomy is the standard for curative management of locally advanced oesophageal cancer. Oesophagectomy is a technically challenging procedure, and is associated with considerable morbidity and mortality despite implementation of minimally invasive techniques.…”
Section: Introductionmentioning
confidence: 99%
“…F o r l o c a l i z e d e s o p h a g e a l c a n c e r, n e o a d j u v a n t chemoradiotherapy or perioperative chemotherapy followed by esophagectomy is increasingly applied worldwide as the curative treatment trajectory (11), with a 5-year disease survival rate around 50% (12).…”
Section: Introductionmentioning
confidence: 99%
“…ESCC is the main pathological type of esophageal cancer in China (2). At present, the primary treatment of esophageal cancer is a comprehensive treatment that is based on surgical treatment, combined with chemotherapy, radiotherapy, chemoradiotherapy or immunotherapy (3). Although the cure rate of early esophageal cancer through endoscopic surgery has reached >90%, early esophageal cancer was diagnosed less frequently (4).…”
Section: Discussionmentioning
confidence: 99%
“…Patients often experience distant metastasis or local disease recurrence, even after undergoing curative resection. Although multi-modality approaches based on surgery combined with preoperative chemotherapy and/or radiotherapy have been attempted, the efficacy of these treatments is limited, and overall survival remains poor (3)(4)(5)(6). Therefore, novel strategies against esophageal cancer need to be developed and established to improve the prognosis of patients.…”
Section: Introductionmentioning
confidence: 99%