Surgical Treatment of Central Giant Cells Lesions in the Maxilla: Case Report

Sarmento, Dmitry José de Santana; Santos, Jalber Almeida dos; Lima, Lúcia Helena Marques de Almeida; Lima, Marcelino Guedes de; Godoy, Gustavo Pina

doi:10.1016/s1808-8694(15)30956-3

Cited by 4 publications

(5 citation statements)

References 3 publications

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“…[2] In the case presented, the mucosa under which was the lesion presented itself intact and consistent to palpation. However, teeth involved by the injury had marked mobility.…”

Section: Discussionmentioning

confidence: 56%

“…It may be isolated or in combination with other lesions, [1] and its conclusive diagnosis depends on histopathological examination. [2] It is extremely important to know the variation of radiological images produced by CGCL. [3,4] Among its characteristics is the presence of a bony granular pattern in the expanded periphery and in the internal septa.…”

Section: Introductionmentioning

confidence: 99%

“…[6] In cases of isolated CGCL, the treatment of choice should be carefully defi ned in accordance with the peculiarities of each case. [2] Because it is a benign lesion, the correct diagnosis avoids mutilating radical treatments. The curettage is still widely used with high success rate.…”

Section: Introductionmentioning

confidence: 99%

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Treatment of an aggressive central giant cell lesion

Volpato¹,

Borba²,

Carvalho³

et al. 2015

SJOD

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Central giant cell lesion (CGCL) is an uncommon alteration of obscure etiology that, although benign, can be highly destructive. This paper presents the case of a patient with CGCL addressing its diagnosis and treatment. An 18-year-old male patient with facial asymmetry due to signifi cant volumetric increase in the right parotidmasseteric and submandibular regions with 9 months of evolution attended the Department of Dentistry of Mato Grosso Cancer Hospital. After clinical and imaginological examinations, an incisional biopsy was performed leading to the diagnostic of CGCL. With the negative results for hyperparathyroidism, the lesion reduction was attempted with corticosteroids infi ltrations. Due to the lesion extension and the lack of response to the infi ltrations, the resection was performed. The patient is in attendance for 2 years without any symptoms of recurrence. Although more prevalent among female, young adults and elderly, the CGCL may present in other patients and the professional must be aware. The therapy of choice in this pathology varies with the aggressiveness and extension of the lesion. More aggressive lesions can lead to more extreme clinical management and involve the need for surgical resection.

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“…[2] In the case presented, the mucosa under which was the lesion presented itself intact and consistent to palpation. However, teeth involved by the injury had marked mobility.…”

Section: Discussionmentioning

confidence: 56%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Treatment of an aggressive central giant cell lesion

Volpato¹,

Borba²,

Carvalho³

et al. 2015

SJOD

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show abstract

“…No diagnostico diferencial dessa patologia pode ser citado o ameloblastoma, queratocisto e o cisto osséo aneurismático 4 . O tratamento deve ser embasado de acordo como a lesão se apresenta, variando desde uma enucleação e curetagem até ressecções em bloco seguidas de enxerto ósseo para os casos mais agressivos 5,6 .…”

Section: A Lesão Central De Células Gigantes ( Lccg) Ou Granuloma Cenunclassified

Cisto ósseo aneurismático secundário a lesão central de células gigantes: relato de caso

Oliveira

Gasperini

Toledo

et al. 2019

BJHR

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“…Clinical, radiographic, and histological characteristics differentiate their level of aggressiveness and guide the treatment plan [1, 2, 5]. In image examinations, CGCL appears as a variation of small apical lesions to large radiolucent areas, which can be unilocular or multilocular, with a slight opacification within the lesion [1, 6]. On histological examination, CGCL consists of cellular fibrous tissue with multiple foci of hemorrhage, multinucleated giant cell aggregates and, occasionally, trabecular bone tissue [4, 7].…”

Section: Introductionmentioning

confidence: 99%

Combination therapies for the treatment of recurrent central giant cell lesion in the maxilla: a case report

et al. 2017

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BackgroundCentral giant cell lesion is a non-neoplastic proliferation, usually asymptomatic, of unknown etiology. The purpose of this case report is to report the diagnosis and the treatment of a recurrent central giant cell lesion in the maxilla.Case presentationA 31-year-old Brazilian woman presented to our Surgery Service for evaluation of a cystic lesion in her teeth 13 and 15, although she had previously received endodontic treatment for her teeth 13 and 15 without regression of the lesion. On clinical examination, an increase and painless swelling was observed in her right jaw. An excisional biopsy of the lesion was performed under general anesthesia; the material was sent for pathological examination and a diagnosis compatible with central giant cell lesion was made. She presented again, 10 months after the removal of the lesion, with a recurrent lesion that surrounded her incisors, canine, and right premolar. We suggested that she underwent treatment with intralesional corticosteroids injection. The lesion was significantly reduced and the remainder of the lesion was enucleated. She is monitored at 3-month intervals; at 6 months postoperatively there has been no recurrence.ConclusionsCentral giant cell lesion can have a high degree of invasiveness, which increases the importance of early diagnosis. Combination therapies can provide a favorable prognosis. Periodic monitoring is recommended, thus avoiding the chance of a relapse.

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Surgical Treatment of Central Giant Cells Lesions in the Maxilla: Case Report

Cited by 4 publications

References 3 publications

Treatment of an aggressive central giant cell lesion

Treatment of an aggressive central giant cell lesion

Cisto ósseo aneurismático secundário a lesão central de células gigantes: relato de caso

Combination therapies for the treatment of recurrent central giant cell lesion in the maxilla: a case report

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